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Trajectory of COVID-19 Vaccine Hesitancy Over Time and Association of Initial Vaccine Hesitancy With Subsequent Vaccination

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To identify the key insights or developments described in this article
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Accepted for Publication: July 25, 2021.

Published: September 24, 2021. doi:10.1001/jamanetworkopen.2021.26882

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Siegler AJ et al. JAMA Network Open.

Corresponding Author: Aaron J. Siegler, MHS, PhD, Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA 30322 (asiegle@emory.edu).

Author Contributions: Dr Siegler had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Siegler, Luisi, Sanchez, Lopman, Sullivan.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Siegler, Hall, Sullivan.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Siegler, Luisi, Hall, Bradley.

Obtained funding: Siegler, Lopman, Sullivan.

Administrative, technical, or material support: Luisi, Sanchez, Lopman.

Supervision: Siegler, Sanchez, Sullivan.

Conflict of Interest Disclosures: Dr Siegler reported receiving grants from the National Institutes of Health (NIH) and the Woodruff Foundation paid to his institution during the conduct of the study. Dr Sanchez reported receiving grants from the NIH during the conduct of the study. Dr Sullivan reported receiving grants and personal fees from the NIH during the conduct of the study, grants and personal fees from the Centers for Disease Control and Prevention, and grants from Gilead Sciences outside the submitted work. No other disclosures were reported.

Funding/Support: Salesforce donated licenses and system development, and the Kaiser Family Foundation provided design contributions. This study was supported by the National Institute of Allergy and Infectious Diseases (grant 3R01AI143875-02S1 to Dr Siegler).

Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Additional Contributions: We appreciate and acknowledge the contributions of our study participants. Mariah Valentine-Graves, MPH, Palmer Ramsay-Hipp, MPH, Radhika Prakash Asrani, MPH, and Ryan Zahn, MPH (all from Emory University), provided project management support, including participant management; they were not compensated beyond their normal salaries.

References
1.
Gharpure  R , Patel  A , Link-Gelles  R .  First-dose COVID-19 vaccination coverage among skilled nursing facility residents and staff.   JAMA. 2021;325(16):1670-1671. doi:10.1001/jama.2021.2352PubMedGoogle ScholarCrossref
2.
Murphy  J , Vallières  F , Bentall  RP ,  et al.  Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom.   Nat Commun. 2021;12(1):29. doi:10.1038/s41467-020-20226-9PubMedGoogle ScholarCrossref
3.
Siegler  AJ , Sullivan  PS , Sanchez  T ,  et al.  Protocol for a national probability survey using home specimen collection methods to assess prevalence and incidence of SARS-CoV-2 infection and antibody response.   Ann Epidemiol. 2020;49:50-60. doi:10.1016/j.annepidem.2020.07.015PubMedGoogle ScholarCrossref
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