Rapidly Enlarging Neck Mass in a Patient With Testicular Cancer | Oncology | JN Learning | AMA Ed Hub [Skip to Content]
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Rapidly Enlarging Neck Mass in a Patient With Testicular Cancer

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

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Article Information

Corresponding Author: Jeremiah C. Tracy, MD, Department of Otolaryngology–Head and Neck Surgery, Tufts Medical Center, 800 Washington St, Box 850, Boston, MA 02111 (jtracy@tuftsmedicalcenter.org).

Published Online: September 23, 2021. doi:10.1001/jamaoto.2021.2420

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

References
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Lee  DJ , Djaladat  H , Tadros  NN ,  et al.  Growing teratoma syndrome: clinical and radiographic characteristics.   Int J Urol. 2014;21(9):905-908. doi:10.1111/iju.12466PubMedGoogle ScholarCrossref
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Nimkin  K , Gupta  P , McCauley  R , Gilchrist  BF , Lessin  MS .  The growing teratoma syndrome.   Pediatr Radiol. 2004;34(3):259-262. doi:10.1007/s00247-003-1045-zPubMedGoogle ScholarCrossref
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Nassiri  N , Shah  A , Daneshmand  S .  Growing teratoma syndrome of testicular origin.   Urology. 2019;123:20-23. doi:10.1016/j.urology.2018.05.015PubMedGoogle ScholarCrossref
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Hiester  A , Nettersheim  D , Nini  A , Lusch  A , Albers  P .  Management, treatment, and molecular background of the growing teratoma syndrome.   Urol Clin North Am. 2019;46(3):419-427. doi:10.1016/j.ucl.2019.04.008PubMedGoogle ScholarCrossref
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Laguna  M , Albers  P , Algaba  F ,  et al. EAU guidelines on testicular cancer. Accessed August 17, 2021. https://uroweb.org/wp-content/uploads/EAU-Guidelines-on-Testicular-Cancer-2020.pdf
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Kesler  KA , Patel  JB , Kruter  LE ,  et al.  The “growing teratoma syndrome” in primary mediastinal nonseminomatous germ cell tumors: criteria based on current practice.   J Thorac Cardiovasc Surg. 2012;144(2):438-443. doi:10.1016/j.jtcvs.2012.05.053PubMedGoogle ScholarCrossref
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André  F , Fizazi  K , Culine  S ,  et al.  The growing teratoma syndrome: results of therapy and long-term follow-up of 33 patients.   Eur J Cancer. 2000;36(11):1389-1394. doi:10.1016/S0959-8049(00)00137-4PubMedGoogle ScholarCrossref
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Motzer  RJ , Amsterdam  A , Prieto  V ,  et al.  Teratoma with malignant transformation: diverse malignant histologies arising in men with germ cell tumors.   J Urol. 1998;159(1):133-138. doi:10.1016/S0022-5347(01)64035-7PubMedGoogle ScholarCrossref
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Jones  TD , Wang  M , Sung  MT ,  et al.  Clonal origin of metastatic testicular teratomas.   Clin Cancer Res. 2006;12(18):5377-5383. doi:10.1158/1078-0432.CCR-06-0444PubMedGoogle ScholarCrossref
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