Widespread Erythematous Plaques With Prominent Telangiectases | Dermatology | JN Learning | AMA Ed Hub [Skip to Content]
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Widespread Erythematous Plaques With Prominent Telangiectases

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
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Article Information

Corresponding Author: Ayan Kusari, MD, Department of Dermatology, University of California, San Francisco School of Medicine, 1701 Divisadero St, 4th Floor, San Francisco, CA 94115 (ayan.kusari@ucsf.edu).

Published Online: October 13, 2021. doi:10.1001/jamadermatol.2021.4068

Conflict of Interest Disclosures: Dr Haemel reported personal fees from CSL Behring for serving on a data and safety monitoring board and from Guidepoint Global for serving as a consultant outside the submitted work. No other disclosures were reported.

Additional Contributions: We thank the patient for granting permission to publish this information. We also thank Ritesh Agnihothri, MD, for providing the clinical image.

References
1.
Ferreri  AJ , Campo  E , Seymour  JF ,  et al; International Extranodal Lymphoma Study Group (IELSG).  Intravascular lymphoma.   Br J Haematol. 2004;127(2):173-183.PubMedGoogle ScholarCrossref
2.
Röglin  J , Böer  A .  Skin manifestations of intravascular lymphoma mimic inflammatory diseases of the skin.   Br J Dermatol. 2007;157(1):16-25.PubMedGoogle ScholarCrossref
3.
Sitthinamsuwan  P , Chinthammitr  Y , Pattanaprichakul  P , Sukpanichnant  S .  Random skin biopsy in the diagnosis of intravascular lymphoma.   J Cutan Pathol. 2017;44(9):729-733.PubMedGoogle ScholarCrossref
4.
Namekawa  M , Nakano  I .  Diagnosis of intravascular lymphoma.  Article in Japanese.  Brain Nerve. 2011;63(5):451-458.PubMedGoogle Scholar
5.
Matsue  K , Abe  Y , Kitadate  A ,  et al.  Sensitivity and specificity of incisional random skin biopsy for diagnosis of intravascular large B-cell lymphoma.   Blood. 2019;133(11):1257-1259.PubMedGoogle ScholarCrossref
6.
Hope  CB , Pincus  LB .  Primary cutaneous B-cell lymphomas with large cell predominance–primary cutaneous follicle center lymphoma, diffuse large B-cell lymphoma, leg type and intravascular large B-cell lymphoma.   Semin Diagn Pathol. 2017;34(1):85-98.PubMedGoogle ScholarCrossref
7.
Adachi  Y , Kosami  K , Mizuta  N ,  et al.  Benefits of skin biopsy of senile hemangioma in intravascular large B-cell lymphoma.   Oncol Lett. 2014;7(6):2003-2006.PubMedGoogle ScholarCrossref
8.
Kwong  Y-L , Kim  WS , Lim  ST ,  et al.  SMILE for natural killer/T-cell lymphoma.   Blood. 2012;120(15):2973-2980.PubMedGoogle ScholarCrossref
9.
Wang  L , Li  L-R , Zhang  L , Wang  J-W .  The landscape of new drugs in extranodal NK/T-cell lymphoma.   Cancer Treat Rev. 2020;89:102065.PubMedGoogle Scholar
10.
Wei  W , Wu  P , Li  L , Zhang  ZH .  Effectiveness of pegaspargase, gemcitabine, and oxaliplatin (P-GEMOX) chemotherapy combined with radiotherapy in newly diagnosed, stage IE to IIE, nasal-type, extranodal natural killer/T-cell lymphoma.   Hematology. 2017;22(6):320-329.PubMedGoogle ScholarCrossref
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