Retinal Artery Thrombosis and Aortic Valve Vegetations | Valvular Heart Disease | JN Learning | AMA Ed Hub [Skip to Content]
[Skip to Content Landing]

Retinal Artery Thrombosis and Aortic Valve Vegetations

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

Please finish quiz first before checking answer.

You answered correctly!

Read the answer below and download your certificate.

You answered incorrectly.

Read the discussion below and retake the quiz.

Survey Complete!

Sign in to take quiz and track your certificates

Buy This Activity

JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 CME Credit™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC

Article Information

Corresponding Author: Miroslav Sekulic, MD, MA, Department of Pathology and Cell Biology, Columbia University Irving Medical Center, 630 W 168th St, VC14-238C, New York, NY 10032 (ms6105@cumc.columbia.edu).

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for providing permission to share her information.

References
1.
Miyakis  S , Lockshin  MD , Atsumi  T ,  et al.  International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).   J Thromb Haemost. 2006;4(2):295-306. doi:10.1111/j.1538-7836.2006.01753.xPubMedGoogle ScholarCrossref
2.
Corban  MT , Duarte-Garcia  A , McBane  RD , Matteson  EL , Lerman  LO , Lerman  A .  Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics.   J Am Coll Cardiol. 2017;69(18):2317-2330. doi:10.1016/j.jacc.2017.02.058PubMedGoogle ScholarCrossref
3.
Eiken  PW , Edwards  WD , Tazelaar  HD , McBane  RD , Zehr  KJ .  Surgical pathology of nonbacterial thrombotic endocarditis in 30 patients, 1985-2000.   Mayo Clin Proc. 2001;76(12):1204-1212. doi:10.4065/76.12.1204PubMedGoogle ScholarCrossref
4.
Izzedine  H , Perazella  MA .  Thrombotic microangiopathy, cancer, and cancer drugs.   Am J Kidney Dis. 2015;66(5):857-868. doi:10.1053/j.ajkd.2015.02.340PubMedGoogle ScholarCrossref
5.
Petri  M , Orbai  AM , Alarcón  GS ,  et al.  Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus.   Arthritis Rheum. 2012;64(8):2677-2686. doi:10.1002/art.34473PubMedGoogle ScholarCrossref
6.
Kolitz  T , Shiber  S , Sharabi  I , Winder  A , Zandman-Goddard  G .  Cardiac manifestations of antiphospholipid syndrome with focus on its primary form.   Front Immunol. 2019;10:941. doi:10.3389/fimmu.2019.00941PubMedGoogle ScholarCrossref
7.
Demirci  FY , Küçükkaya  R , Akarçay  K ,  et al.  Ocular involvement in primary antiphospholipid syndrome.   Int Ophthalmol. 1998;22(6):323-329. doi:10.1023/A:1006305705080PubMedGoogle ScholarCrossref
8.
Castañón  C , Amigo  MC , Bañales  JL , Nava  A , Reyes  PA .  Ocular vaso-occlusive disease in primary antiphospholipid syndrome.   Ophthalmology. 1995;102(2):256-262. doi:10.1016/S0161-6420(95)31028-7PubMedGoogle ScholarCrossref
9.
Zmaili  MA , Alzubi  JM , Kocyigit  D ,  et al.  A contemporary 20-year Cleveland Clinic experience of nonbacterial thrombotic endocarditis: etiology, echocardiographic imaging, management, and outcomes.   Am J Med. 2021;134(3):361-369. doi:10.1016/j.amjmed.2020.06.047PubMedGoogle ScholarCrossref
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_Multimedia_LoginSubscribe_Purchase
Close
If you are not a JN Learning subscriber, you can either:
Subscribe to JN Learning for one year
Buy this activity
jn-learning_Modal_Multimedia_LoginSubscribe_Purchase
Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close

Name Your Search

Save Search
Close
With a personal account, you can:
  • Track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
jn-learning_Modal_SaveSearch_NoAccess_Purchase
Close

Lookup An Activity

or

Close

My Saved Searches

You currently have no searches saved.

Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close