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Assessment of Cognitive Function in Patients After COVID-19 Infection

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Accepted for Publication: August 17, 2021.

Published: October 22, 2021. doi:10.1001/jamanetworkopen.2021.30645

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Becker JH et al. JAMA Network Open.

Corresponding Author: Jacqueline H. Becker, PhD, Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029 (jacqueline.becker@mountsinai.org).

Author Contributions: Drs Becker and Wisnivesky had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Becker, Lin, Wisnivesky.

Acquisition, analysis, or interpretation of data: Becker, Doernberg, Stone, Navis, Festa, Wisnivesky.

Drafting of the manuscript: Becker, Stone, Wisnivesky.

Critical revision of the manuscript for important intellectual content: Becker, Lin, Doernberg, Navis, Festa, Wisnivesky.

Statistical analysis: Becker, Stone, Wisnivesky.

Obtained funding: Wisnivesky.

Administrative, technical, or material support: Becker, Lin, Doernberg, Wisnivesky.

Supervision: Becker, Lin, Doernberg, Navis, Wisnivesky.

Conflict of Interest Disclosures: Dr Wisnivesky reported receiving personal fees from Sanofi, Atea Pharmaceuticals, and Banook Group and grants from Sanofi, Regeneron Pharmaceuticals, and Arnold Consulting outside the submitted work. No other disclosures were reported.

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Pandharipande  PP , Girard  TD , Jackson  JC ,  et al; BRAIN-ICU Study Investigators.  Long-term cognitive impairment after critical illness.   N Engl J Med. 2013;369(14):1306-1316. doi:10.1056/NEJMoa1301372PubMedGoogle ScholarCrossref
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Beraki  S , Aronsson  F , Karlsson  H , Ogren  SO , Kristensson  K .  Influenza A virus infection causes alterations in expression of synaptic regulatory genes combined with changes in cognitive and emotional behaviors in mice.   Mol Psychiatry. 2005;10(3):299-308. doi:10.1038/sj.mp.4001545PubMedGoogle ScholarCrossref
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