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Blurry Vision in a Patient With Leukemia

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

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Article Information

Corresponding Author: Danny A. Mammo, MD, Cole Eye Institute, Cleveland Clinic, 2022 E 105th St, I Building, Cleveland, OH 44106 (danny.mammo24@gmail.com).

Published Online: October 21, 2021. doi:10.1001/jamaophthalmol.2021.1456

Conflict of Interest Disclosures: Dr Rachitskaya reported personal fees from Alcon, Allergan, Regeneron, Genentech, Novartis, Samsara, and Zeiss outside the submitted work. Dr Singh reported having stock options in Aura Biosciences and consultancy relationships with IsoAid LLC, Immunocore, Isoaid, and Eckert and Zeigler outside the submitted work. Dr Mammo is supported by the Heed Ophthalmic Foundation outside the submitted work.

Additional Contributions: We thank the patient for granting permission to publish this information.

References
1.
Horton  JC , Garcia  EC , Becker  EK .  Magnetic resonance imaging of leukemic invasion of the optic nerve.   Arch Ophthalmol. 1992;110(9):1207-1208. doi:10.1001/archopht.1992.01080210025010 PubMedGoogle ScholarCrossref
2.
Czorlich  P , Skevas  C , Knospe  V ,  et al.  Terson syndrome in subarachnoid hemorrhage, intracerebral hemorrhage, and traumatic brain injury.   Neurosurg Rev. 2015;38(1):129-136. doi:10.1007/s10143-014-0564-4 PubMedGoogle ScholarCrossref
3.
Tarlan  B , Kiratli  H .  Intraocular Manifestations of Hematopoietic Disorders. Springer Nature; 2019. doi:10.1007/978-3-030-17879-6_25
4.
Damato  BE , Singh  AD , eds.  Clinical Ophthalmic Oncology: Uveal Tumors. Vol 25. Springer; 2019:365-378. doi:10.1007/978-3-030-17879-6
5.
Myers  KA , Nikolic  A , Romanchuk  K ,  et al.  Optic neuropathy in the context of leukemia or lymphoma: diagnostic approach to a neuro-oncologic emergency.   Neurooncol Pract. 2017;4(1):60-66. doi:10.1093/nop/npw006 PubMedGoogle Scholar
6.
Gnanaraj  L , Tyagi  AK , Cottrell  DG ,  et al.  Referral delay and ocular surgical outcome in Terson syndrome.   Retina. 2000;20(4):374-377. doi:10.1097/00006982-200007000-00009 PubMedGoogle ScholarCrossref
7.
Narayanan  R , Taylor  SC , Nayaka  A ,  et al.  Visual outcomes after vitrectomy for Terson syndrome secondary to traumatic brain injury.   Ophthalmology. 2017;124(1):118-122. doi:10.1016/j.ophtha.2016.09.009 PubMedGoogle ScholarCrossref
8.
Chen  C-Y , Tai  C-H , Cheng  A ,  et al.  Intracranial hemorrhage in adult patients with hematological malignancies.   BMC Med. 2012;10(1):97. doi:10.1186/1741-7015-10-97 PubMedGoogle ScholarCrossref
9.
Lorenzi  U , Buschini  E , Fea  A , Machetta  F , Grignolo  FM .  Terson syndrome and leukemia: a case report.   Clin Ophthalmol. 2014;8:681-683.PubMedGoogle Scholar
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