Accepted for Publication: November 2, 2021.
Published: December 28, 2021. doi:10.1001/jamanetworkopen.2021.40875
Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2021 Li X et al. JAMA Network Open.
Corresponding Author: Xuedi Li, MSc, Child Health Evaluative Sciences, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, 686 Bay St, Toronto, ON M5G 0A4, Canada (xuedi.li@sickkids.ca).
Author Contributions: Drs Korczak and Birken had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Li, Vanderloo, Keown-Stoneman, Charach, Maguire, Monga, Crosbie, Anagnostou, Georgiades, Korczak, Birken.
Acquisition, analysis, or interpretation of data: Li, Keown-Stoneman, Cost, Monga, Crosbie, Burton, Anagnostou, Georgiades, Nicolson, Kelley, Ayub, Korczak, Birken.
Drafting of the manuscript: Li, Vanderloo, Keown-Stoneman, Crosbie.
Critical revision of the manuscript for important intellectual content: Vanderloo, Keown-Stoneman, Cost, Charach, Maguire, Monga, Crosbie, Burton, Anagnostou, Georgiades, Nicolson, Kelley, Ayub, Korczak, Birken.
Statistical analysis: Li, Keown-Stoneman, Cost, Crosbie, Anagnostou.
Obtained funding: Keown-Stoneman, Maguire, Monga, Crosbie, Burton, Anagnostou, Georgiades, Kelley, Korczak, Birken.
Administrative, technical, or material support: Vanderloo, Keown-Stoneman, Maguire, Burton, Anagnostou, Georgiades, Ayub.
Supervision: Vanderloo, Keown-Stoneman, Maguire, Anagnostou, Georgiades, Korczak, Birken.
Conflict of Interest Disclosures: Dr Charach reported receiving grants from SickKids Hospital and Leong Centre for Healthy Children and in-kind support for all POND data from the Ontario Brain Institute during the conduct of the study. Dr Monga reported receiving grants from Cundill Centre for Youth Depression at the Centre for Addiction and Mental Health, book royalties from Springer Publishers, and grants from Canadian Institutes of Health Research outside the submitted work. Dr Anagnostou reported receiving consultation fees from Roche and Quadrant, research funding from Roche, in-kind support from AMO pharma, editorial honoraria from Wiley, and book royalties from APPI and Springer; she also holds a patent for the device Tully (formerly Anxiety Meter). Dr Nicolson reported receiving grants from Ontario Brain Institute during the conduct of the study. Dr Kelley reported receiving grants from Ontario Brain Institute, Canadian Institutes of Health Research, and the Masonic Foundation of Ontario outside the submitted work. No other disclosures were reported.
Funding/Support: This study was supported by the Canadian Institutes of Health Research (grant 173092), the Centre for Brain & Mental Health at The Hospital for Sick Children, the Ontario Ministry of Health (grant 700), and the Miner’s Lamp Innovation Fund in Prevention and Early Detection of Severe Mental Illness at the University of Toronto.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank all the participating families for their time and involvement in this research and are grateful to all practitioners who are currently involved in the TARGetKids! practice-based research network.