A man in his 60s presented with a 20-year history of progressive pruritic skin lesions on his face and trunk. The lesions first appeared on his back without identifiable cause and spread, reaching the abdomen and eventually the head and face. Skin examination revealed multiple edematous red plaques distributed over the patient’s forehead, eyelids, and chin that were accompanied by alopecia of the right eyebrow (Figure, A). These plaques were ill-defined, ranging from 3 cm to 6 cm in diameter. Simultaneously, we could identify generalized follicular red papules on his abdomen, back, and both sides of the chest (Figure, B). The papules were 2 mm in size and partially fused into red patches. Punch biopsies were performed from the chin and back, the results revealing dense and deep infiltration of lymphocytes in and around hair follicles. Immunohistochemical staining showed that the infiltrating cells expressed CD3 and CD4, while CD8 and CD56 were negative. His baseline laboratory investigations yielded normal results. His workup results were negative for extracutaneous involvement. The diagnosis of skin-limited folliculotropic mycosis fungoides (FMF) was established. The skin lesions achieved partial remission following treatment with interferon α (IFNa) injection and UV-B phototherapy.