Type 1 diabetes (T1D) is a disorder of autoimmune-mediated pancreatic β-cell destruction and decreased insulin production. Although the incidence of this disease is increasing globally each year,1 our local experience at Rady Children’s Hospital San Diego, the tertiary care center for children in San Diego, California, and surrounding counties, was that the incidence of new-onset T1D during the COVID-19 global pandemic in 2020 and 2021 appeared to have increased compared with previous years. We performed a 6-year retrospective review of the medical record to evaluate whether the perceived increased incidence was significant and whether or not more children had diabetic ketoacidosis (DKA) at presentation or required pediatric intensive care unit (PICU) admission (at our institution for altered mental status or severe acidosis only) as a measure of the severity of illness at diabetes onset.
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Accepted for Publication: October 12, 2021.
Published Online: January 24, 2022. doi:10.1001/jamapediatrics.2021.5801
Corresponding Author: Jane J. Kim, MD, Department of Pediatrics, University of California, San Diego, 3020 Children’s Way, MC 5103, San Diego, CA 92123 (firstname.lastname@example.org).
Author Contributions: Drs Gottesman and Kim had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Concept and design: Gottesman, Longhurst, Kim.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Gottesman, Yu, Tanaka, Kim.
Critical revision of the manuscript for important intellectual content: Gottesman, Yu, Longhurst, Kim.
Statistical analysis: Gottesman, Yu, Kim.
Administrative, technical, or material support: Gottesman, Longhurst.
Supervision: Longhurst, Kim.
Conflict of Interest Disclosures: None reported.
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