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Sexually Transmitted Infections

CDC Sexually Transmitted Infections Treatment Guidelines, 2021

Educational Objective
To identify the key insights or developments described in this article

1 Credit CME

JAMA

Published Online: March 1, 2022

JAMA Clinical Guidelines Synopsis

Article Information and Disclosures

Aniruddha Hazra, MD¹;

Maggie W. Collison, MD²;

Andrew M. Davis, MD, MPH³

Author Affiliations

¹Section of Infectious Diseases and Global Health, University of Chicago Medicine, Chicago, Illinois
²Division of Infectious Disease, NorthShore University HealthSystem, Evanston, Illinois
³Section of General Internal Medicine, University of Chicago Medicine, Chicago, Illinois

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The 2019 CDC STD Surveillance Report found that the annual cases of STIs in the US continued to increase in 2019, totaling more than an estimated 2.5 million cases of chlamydia, gonorrhea, and syphilis; congenital syphilis increased by 279% between 2015 and 2019.¹ STIs have increased across multiple groups, but disproportionately affect racial and ethnic minority groups, gay and bisexual men, and youth.² These guidelines address STI topics including general prevention, vaccination, appropriate sexual history taking, screening, treatment, and partner therapy.³

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Article Information

Corresponding Author: Andrew M. Davis, MD, MPH, University of Chicago Medicine, 5841 S Maryland Ave, Chicago, IL 60637 (amd@uchicago.edu).

Conflict of Interest Disclosures: Dr Hazra reported receiving grants from Gilead Sciences. No other disclosures were reported.

References

Centers for Disease Control and Prevention. Sexually transmitted disease surveillance 2019. Accessed December 9, 2021. https://www.cdc.gov/std/statistics/2019/default.htm

National Academies of Sciences, Engineering, and Medicine. Sexually Transmitted Infections. National Academies Press; 2021.

Workowski KA , Bachmann LH , Chan PA , et al. Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021;70(4):1-187.PubMed Google Scholar Crossref

Murray GL , Bradshaw CS , Bissessor M , et al. Increasing macrolide and fluoroquinolone resistance in Mycoplasma genitalium. Emerg Infect Dis. 2017;23(5):809-812.PubMed Google Scholar Crossref

Tuddenham S , Hamill MM , Ghanem KG . Diagnosis and treatment of sexually transmitted infections: a review. JAMA. 2022;327(2):161-172.PubMed Google Scholar Crossref

Eckman MH , Reed JL , Trent M , Goyal MK . Cost-effectiveness of sexually transmitted infection screening for adolescents and young adults in the pediatric emergency department. JAMA Pediatr. 2021;175(1):81-89.PubMed Google Scholar Crossref

Stanford KA , Hazra A , Friedman E , et al. Opt-out, routine emergency department syphilis screening as a novel intervention in at-risk populations. Sex Transm Dis. 2021;48(5):347-352.PubMed Google Scholar Crossref

Gilbert L , Goddard-Eckrich D , Chang M , et al. Effectiveness of a culturally tailored HIV and sexually transmitted infection prevention intervention for Black women in community supervision programs. JAMA Netw Open. 2021;4(4):e215226.PubMed Google Scholar

Kersh EN , Shukla M , Raphael BH , Habel M , Park I . At-home specimen self-collection and self-testing for STI screening demand accelerated by the COVID-19 pandemic. J Clin Microbiol. 2021;59(11):e0264620.PubMed Google Scholar

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.