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Infectious Diseases

Clinical Guideline Synopsis of Evaluation and Management of Well-Appearing Febrile Infants Aged 8 to 60 Days

Educational Objective
To identify the key insights or developments described in this article

1 Credit CME

JAMA Pediatrics

Published Online: March 14, 2022

JAMA Network Clinical Guideline Synopsis

Article Information and Disclosures

Eileen Murtagh Kurowski, MD, MS^1,2;

Seema Bhatt, MD, MS^1,2;

Scott Reeves, MD^1,2

Author Affiliations

¹Division of Emergency Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
²Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio

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Article Information

Corresponding Author: Eileen Murtagh Kurowski, MD, MS, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, MLC 2008 Cincinnati, OH 45229-3039 (eileen.murtagh-kurowski@cchmc.org).

Published Online: March 14, 2022. doi:10.1001/jamapediatrics.2022.0066

Conflict of Interest Disclosures: None reported.

References

Aronson PL , Thurm C , Alpern ER , et al; Febrile Young Infant Research Collaborative. Variation in care of the febrile young infant <90 days in US pediatric emergency departments. Pediatrics. 2014;134(4):667-677. doi:10.1542/peds.2014-1382 PubMed Google Scholar Crossref

Powell EC , Mahajan PV , Roosevelt G , et al; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). Epidemiology of bacteremia in febrile infants aged 60 days and younger. Ann Emerg Med. 2018;71(2):211-216. doi:10.1016/j.annemergmed.2017.07.488 PubMed Google Scholar Crossref

Gomez B , Mintegi S , Bressan S , Da Dalt L , Gervaix A , Lacroix L ; European Group for Validation of the Step-by-Step Approach. Validation of the “step-by-step” approach in the management of young febrile infants. Pediatrics. 2016;138(2):e20154381. doi:10.1542/peds.2015-4381 PubMed Google Scholar Crossref

Kuppermann N , Dayan PS , Levine DA , et al; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). A clinical prediction rule to identify febrile infants 60 days and younger at low risk for serious bacterial infections. JAMA Pediatr. 2019;173(4):342-351. doi:10.1001/jamapediatrics.2018.5501 PubMed Google Scholar Crossref

Hui C , Neto G , Tsertsvadze A , et al. Diagnosis and management of febrile infants (0-3 months). Evid Rep Technol Assess (Full Rep). 2012;(205):1-297.PubMed Google Scholar

Ladhani SN , Henderson KL , Muller-Pebody B , Ramsay ME , Riordan A . Risk of invasive bacterial infections by week of age in infants. Arch Dis Child. 2019;104(9):874-878. doi:10.1136/archdischild-2018-316191 PubMed Google Scholar Crossref

Aronson PL , Schaeffer P , Niccolai LM , Shapiro ED , Fraenkel L . Parents’ perspectives on communication and shared decision making for febrile infants ≤60 days old. Pediatr Emerg Care. 2021;37(12):e1213-e1219.PubMed Google Scholar Crossref

Aronson PL , Shabanova V , Shapiro ED , et al; Febrile Young Infant Research Collaborative. A prediction model to identify febrile infants ≤60 days at low risk of invasive bacterial infection. Pediatrics. 2019;144(1):e20183604. doi:10.1542/peds.2018-3604 PubMed Google Scholar Crossref

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.