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Occupation and Educational Attainment Characteristics Associated With COVID-19 Mortality by Race and Ethnicity in California

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME
Key Points

Question  To what extent are inequities in educational attainment and occupational characteristics associated with racial and ethnic inequities in COVID-19 mortality?

Findings  In this cohort study of 25 million working-age adults in California, differences in the distribution of education and occupation across racial and ethnic groups were associated with racial and ethnic inequities in COVID-19 mortality, particularly for Latinx adults. If every working-age Californian had the COVID-19 mortality risk associated with the lowest-risk educational and occupational position, there would have been an estimated 8441 (43%) fewer deaths in this population.

Meaning  Educational and occupational disadvantage are important factors associated with risk for COVID-19 mortality, but eliminating avoidable excess risk associated with low-education, essential, on-site, and low-wage jobs is unlikely to be sufficient alone to achieve equity.

Abstract

Importance  Racial and ethnic inequities in COVID-19 mortality may be driven by occupation and education, but limited evidence has assessed these mechanisms.

Objective  To estimate whether occupational characteristics or educational attainment explained the associations between race and ethnicity and COVID-19 mortality.

Design, Setting, and Participants  This population-based retrospective cohort study of Californians aged 18 to 65 years linked COVID-19 deaths to population estimates within strata defined by race and ethnicity, gender, age, nativity in the US, region of residence, education, and occupation. Analysis was conducted from September 2020 to February 2022.

Exposures  Education and occupational characteristics associated with COVID-19 exposure (essential sector, telework option, wages).

Main Outcomes and Measures  All confirmed COVID-19 deaths in California through February 12, 2021. The study estimated what COVID-19 mortality would have been if each racial and ethnic group had (1) the COVID-19 mortality risk associated with the education and occupation distribution of White people and (2) the COVID-19 mortality risk associated with the lowest-risk educational and occupational positions.

Results  Of 25 235 092 participants (mean [SD] age, 40 [14] years; 12 730 395 [50%] men), 14 783 died of COVID-19, 8 125 565 (32%) had a Bachelor’s degree or higher, 13 345 829 (53%) worked in essential sectors, 11 783 017 (47%) could not telework, and 12 812 095 (51%) had annual wages under $51 700. COVID-19 mortality ranged from 15 deaths per 100 000 for White women and Asian women to 139 deaths per 100 000 for Latinx men. Accounting for differences in age, nativity, and region of residence, if all races and ethnicities had the COVID-19 mortality associated with the occupational characteristics of White people (sector, telework, wages), COVID-19 mortality would be reduced by 10% (95% CI, 6% to 14%) for Latinx men, but increased by 5% (95% CI, −8% to 17%) for Black men. If all working-age Californians had the COVID-19 mortality associated with the lowest-risk educational and occupational position (Bachelor’s degree, nonessential, telework, and highest wage quintile), there would have been 43% fewer COVID-19 deaths among working-age adults (8441 fewer deaths; 95% CI, 32%-54%), with the largest absolute risk reductions for Latinx men (3755 deaths averted; 95% CI, 3304-4255 deaths) and Latinx women (2329 deaths averted; 95% CI, 2038-2621 deaths).

Conclusions and Relevance  In this population-based cohort study of working-age California adults, occupational disadvantage was associated with excess COVID-19 mortality for Latinx men. For all racial and ethnic groups, excess risk associated with low-education, essential, on-site, and low-wage jobs accounted for a substantial fraction of COVID-19 mortality.

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Article Information

Accepted for Publication: March 3, 2022.

Published: April 22, 2022. doi:10.1001/jamanetworkopen.2022.8406

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2022 Matthay EC et al. JAMA Network Open.

Corresponding Author: Ellicott C. Matthay, PhD, Center for Health and Community, University of California, San Francisco, 550 16th St, 2nd Flr, Campus Box 0560, San Francisco, CA 94143 (ellicott.matthay@ucsf.edu).

Author Contributions: Dr Matthay had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Drs Duchowny and Riley contributed equally to this work.

Concept and design: Matthay, Duchowny, Riley, Thomas, Glymour.

Acquisition, analysis, or interpretation of data: All authors.

Drafting of the manuscript: Matthay, Duchowny, Riley, Thomas.

Critical revision of the manuscript for important intellectual content: All authors.

Statistical analysis: Matthay, Duchowny.

Obtained funding: Matthay, Bibbins-Domingo.

Administrative, technical, or material support: Duchowny, Thomas, Bibbins-Domingo.

Supervision: Bibbins-Domingo.

Conflict of Interest Disclosures: Dr Glymour reported receiving grants from the National Institutes of Health and National Institute on Aging outside the submitted work. No other disclosures were reported.

Funding/Support: This study was funded by the National Institute on Alcohol Abuse and Alcoholism (grant K99 AA028256) and the National Institute on Aging (grant K99 AG066846).

Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Disclaimer: The content is solely the responsibility of the authors, and does not necessarily represent the official views of the National Institutes of Health or the California Department of Public Health.

Additional Contributions: The California Department of Public Health provided the death data for the study.

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