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Evaluation of Trends in Alcohol Use Disorder–Related Mortality in the US Before and During the COVID-19 Pandemic

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To identify the key insights or developments described in this article

1 Credit CME

JAMA Network Open

Published Online: May 4, 2022

Research Letter

Article Information and Disclosures

Yee Hui Yeo, MD, MSc¹;

Xinyuan He, MD²;

Peng-Sheng Ting, MD³;

Jian Zu, PhD⁴;

Christopher V. Almario, MD⁵;

Brennan M. R. Spiegel, MD⁵;

Fanpu Ji, MD, PhD²

Author Affiliations

¹Division of General Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, California
²Department of Infectious Diseases, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China
³Division of Gastroenterology and Hepatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
⁴School of Mathematics and Statistics, Xi’an Jiaotong University, Xi’an, Shaanxi, China
⁵Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California

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The US mortality rate has surged during the COVID-19 pandemic. Therefore, it is imperative to identify diseases and health conditions that have been affected disproportionately. Mounting evidence indicates that alcohol sales, alcohol consumption, and complications of alcohol use have increased during the pandemic.¹^- 3 However, there are limited data on nationwide alcohol use disorder (AUD)–related mortality. Here, we use projective modeling to evaluate AUD-related mortality rates in the US from 2012 to 2021, with a focus on trends during the COVID-19 pandemic.

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Article Information

Accepted for Publication: March 16, 2022.

Published: May 4, 2022. doi:10.1001/jamanetworkopen.2022.10259

Open Access: This is an open access article distributed under the terms of the CC-BY License. © 2022 Yeo YH et al. JAMA Network Open.

Corresponding Authors: Yee Hui Yeo, MD, MSc, Division of General Internal Medicine, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048 (yeehui.yeo@cshs.org); Fanpu Ji, MD, PhD, Department of Infectious Diseases, Second Affiliated Hospital of Xi’an Jiaotong University, No. 157 Xi Wu Rd, Xi’an 710004, Shaanxi Province, People’s Republic of China (jifanpu1979@163.com or infection@xjtu.edu.cn).

Author Contributions: Drs Yeo and Ji had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Concept and design: Yeo, Almario, Ji.

Acquisition, analysis, or interpretation of data: He, Ting, Zu, Almario, Spiegel, Ji.

Drafting of the manuscript: Yeo, Ting.

Critical revision of the manuscript for important intellectual content: He, Ting, Zu, Almario, Spiegel, Ji.

Statistical analysis: Yeo, He, Zu, Ji.

Administrative, technical, or material support: Zu.

Supervision: Yeo, Zu, Spiegel, Ji.

Conflict of Interest Disclosures: Dr Ji reported receiving speaker fees from and serving on the advisory boards of Gilead Sciences and Merck Sharp & Dohme during the conduct of the study. No other disclosures were reported.

References

Pollard MS , Tucker JS , Green HD Jr . Changes in adult alcohol use and consequences during the COVID-19 pandemic in the US. JAMA Netw Open. 2020;3(9):e2022942. doi:10.1001/jamanetworkopen.2020.22942 PubMed Google Scholar Crossref

Chen PH , Ting PS , Almazan E , Chander G , Cameron AM , Gurakar A . Inter-hospital escalation-of-care referrals for severe alcohol-related liver disease with recent drinking during the COVID-19 pandemic. Alcohol. 2022;57(2):185-189. doi:10.1093/alcalc/agab047 PubMed Google Scholar Crossref

Micallef JV . How the COVID-19 pandemic is upending the alcoholic beverage industry. Forbes. April 4, 2020. Accessed January 10, 2022. https://www.forbes.com/sites/joemicallef/2020/04/04/how-the-covid-19-pandemic-is-upending-the-alcoholic-beverage-industry/?sh=27fe1c5f4b0b

Centers for Disease Control and Prevention. CDC WONDER (Wide-Ranging Online Data for Epidemiologic Research) Database. 2021. Accessed February 15, 2022. https://wonder.cdc.gov/

Murphy SL , Xu J , Kochanek KD , Arias E , Tejada-Vera B . Deaths: final data for 2018. Natl Vital Stat Rep. 2021;69(13):1-83.PubMed Google Scholar

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.