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Unusual Basal Cell Carcinoma in an Adult Woman With Gorlin-Goltz Syndrome

Educational Objective
To identify the key insights or developments described in this article
1 Credit CME

A woman aged 66 years presented to the ophthalmology clinic for evaluation of an asymptomatic medial canthus mass of the left eye (Figure, A). Her medical history was significant for Gorlin-Goltz syndrome. Her best-corrected visual acuity was 6/9 OD and 6/7.5 OS. On examination, the medial canthus mass was noted to be noncontiguous with the periorbital skin. Biopsy of the lesion revealed conjunctival basal cell carcinoma (BCC) (Figure, B). The lesion was managed with 2 excisions and conjunctival patch grafting.

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Cam Loveridge-Easther, MBChB, Unit 5, 11 Parlane St, Addington, Christchurch, New Zealand 8024 (cam.loveridge.easther@gmail.com).

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

References
1.
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Ash  JE .  Epibulbar tumors.   Am J Ophthalmol. 1950;33(8):1203-1219. doi:10.1016/0002-9394(50)90990-1PubMedGoogle ScholarCrossref
3.
Moramarco  A , Himmelblau  E , Miraglia  E ,  et al.  Ocular manifestations in Gorlin-Goltz syndrome.   Orphanet J Rare Dis. 2019;14(1):218. doi:10.1186/s13023-019-1190-6PubMedGoogle ScholarCrossref
4.
Shields  CL , Alset  AE , Boal  NS ,  et al.  Conjunctival tumors in 5002 cases: comparative analysis of benign vs malignant counterparts—the 2016 James D. Allen lecture.   Am J Ophthalmol. 2017;173:106-133. doi:10.1016/j.ajo.2016.09.034PubMedGoogle ScholarCrossref
5.
Mudhar  HS , Roy  SR , Nuruddin  M , Hoque  F .  Primary conjunctival pigmented basal cell carcinoma with increased numbers of intratumour melanocytes, mimicking melanoma: a case report and review of the literature.   Ocul Oncol Pathol. 2020;6(3):168-173. doi:10.1159/000504413PubMedGoogle ScholarCrossref
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