A 42-year-old woman with history of a functional pituitary adenoma, breast cancer in remission for which she was undergoing tamoxifen therapy, and prior bilateral laser in situ keratomileusis surgery was referred for evaluation of right lagophthalmos. She reported 2 months of increasing right-sided blurry vision and a sensation of eye dryness. She was found to have incomplete eyelid closure by her primary care physician, who initiated artificial tear lubrication and bedtime eyelid taping with partial symptom improvement.
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Clinical examination revealed 20/25 visual acuity OD with full extraocular motility and normal intraocular pressure. She was noted to have right upper eyelid retraction (Figure 1A) with substantial static upper eyelid lag on downgaze (Figure 1B). She had 1-mm right lagophthalmos with incomplete blink. Frontalis and orbicularis oculi strength were intact. She was measured to have a 2-mm relative right enophthalmos and no resistance to retropulsion. A review of patient photographs from 2 years prior showed symmetric bilateral eyelid appearance without retraction.
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Natalie A. Homer, MD, UC Davis Health Eye Center, Division of Ophthalmic Plastic and Orbital Surgery, Department of Ophthalmology, University of California, Davis, 4860 Y St, Ste 2400, Sacramento, CA 95817 (email@example.com).
Published Online: June 16, 2022. doi:10.1001/jamaophthalmol.2022.1532
Conflict of Interest Disclosures: Dr Homer reported personal fees as a consultant from Pulse Biosciences outside the submitted work. No other disclosures were reported.
Additional Contributions: We thank the patient for granting permission to publish this information.
Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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