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COVID-19 mRNA Vaccine Booster During Pregnancy Increases Maternal and Fetal Antibodies

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Pregnant individuals who received a booster dose of the BNT162b2 (Pfizer-BioNTech) COVID-19 mRNA vaccine during their second trimester developed higher antibody levels than those who received the second shot in their primary vaccine series during the same trimester, researchers in Israel recently reported in Obstetrics & Gynecology. Infants in the booster group also had higher antibody levels at birth than those in the 2-dose group. The study’s authors say the findings support a COVID-19 maternal booster following full COVID-19 vaccination to protect both pregnant people and their infants.

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Article Information

Published Online: June 22, 2022. doi:10.1001/jama.2022.11145

Conflict of Interest Disclosures: No disclosures were reported.

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