[Skip to Content]
[Skip to Content Landing]

Obesity and Weight Management for Prevention and Treatment of Type 2 Diabetes

To identify the key insights or developments described in this article
1 Credit CME

Type 2 diabetes is a disease characterized by insulin resistance and pancreatic β-cell dysfunction resulting in hyperglycemia. An estimated 34 million people in the US (about 1 in 10) have diabetes, of whom an estimated 90% to 95% have type 2 diabetes.1 The risk of type 2 diabetes increases with obesity, and weight loss is associated with improved glycemic control. Both obesity and type 2 diabetes increase risk of cardiovascular disease, a leading cause of death in the US.

Sign in to take quiz and track your certificates

Buy This Activity

JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 Credit(s)™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC

CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Adam S. Cifu, MD, University of Chicago, 5841 S Maryland Ave, MC 3051, Chicago, IL 60637 (adamcifu@uchicago.edu).

Published Online: July 11, 2022. doi:10.1001/jama.2022.10338

Conflict of Interest Disclosures: None reported.

References
1.
Centers for Disease Control and Prevention. National Diabetes Statistics Report 2020: Estimates of Diabetes and its Burden in the United States. Accessed July 1, 2022. https://www.cdc.gov/diabetes/pdfs/data/statistics/national-diabetes-statistics-report.pdf
2.
Draznin  B , Aroda  VR , Bakris  G ,  et al.  Obesity and weight management for the prevention and treatment of type 2 diabetes: standards of medical care in diabetes—2022.   Diabetes Care. 2022;45(suppl 1):S113-S124. doi:10.2337/dc22-S008PubMedGoogle ScholarCrossref
3.
Franz  MJ , Boucher  JL , Rutten-Ramos  S , VanWormer  JJ .  Lifestyle weight-loss intervention outcomes in overweight and obese adults with type 2 diabetes.   J Acad Nutr Diet. 2015;115(9):1447-1463. doi:10.1016/j.jand.2015.02.031PubMedGoogle ScholarCrossref
4.
Cai  X , Yang  W , Gao  X ,  et al.  Baseline body mass index and the efficacy of hypoglycemic treatment in type 2 diabetes.   PLoS One. 2016;11(12):e0166625. doi:10.1371/journal.pone.0166625PubMedGoogle ScholarCrossref
5.
Ikramuddin  S , Korner  J , Lee  W-J ,  et al.  Durability of addition of Roux-en-Y gastric bypass to lifestyle intervention and medical management in achieving primary treatment goals for uncontrolled type 2 diabetes in mild to moderate obesity.   Diabetes Care. 2016;39(9):1510-1518. doi:10.2337/dc15-2481PubMedGoogle ScholarCrossref
6.
Schauer  PR , Bhatt  DL , Kirwan  JP ,  et al.  Bariatric surgery versus intensive medical therapy for diabetes—5-year outcomes.   N Engl J Med. 2017;376(7):641-651. doi:10.1056/NEJMoa1600869PubMedGoogle ScholarCrossref
7.
Syn  NL , Cummings  DE , Wang  LZ ,  et al.  Association of metabolic-bariatric surgery with long-term survival in adults with and without diabetes.   Lancet. 2021;397(10287):1830-1841. doi:10.1016/S0140-6736(21)00591-2PubMedGoogle ScholarCrossref
8.
Garvey  WT , Mechanick  JI , Brett  EM ,  et al.  American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity.   Endocr Pract. 2016;22(3)(suppl 3):1-203. doi:10.4158/EP161365.GLPubMedGoogle ScholarCrossref
Close
Want full access to the AMA Ed Hub?
After you sign up for AMA Membership, make sure you sign in or create a Physician account with the AMA in order to access all learning activities on the AMA Ed Hub
Buy this activity
Close
Want full access to the AMA Ed Hub?
After you sign up for AMA Membership, make sure you sign in or create a Physician account with the AMA in order to access all learning activities on the AMA Ed Hub
Buy this activity
Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close

Name Your Search

Save Search
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Close
Close

Lookup An Activity

or

My Saved Searches

You currently have no searches saved.

Close

My Saved Courses

You currently have no courses saved.

Close