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Health conditions may cause patients to feel ill and have impaired functioning in their daily lives. Thus, it is important to assess how patients are feeling and functioning when evaluating the effects of interventions to prevent or treat health conditions. Aspects of health that patients can report on directly, such as the severity of pain or limitations in physical functioning, are patient-reported outcomes.
The recommended quantitative approach to measure these aspects of health status is to ask patients directly using a standardized questionnaire. Patient-reported outcome measures are reports of “the status of a patient’s health condition that comes directly from the patient without interpretation of the patient’s response by a clinician or anyone else.”1 An example of a patient-reported outcome measure, the Short Form 36 (SF-36), was used in a randomized clinical trial conducted by Ghogawala et al2 to compare 2 surgical approaches (ventral or dorsal) for the treatment of cervical spondylotic myelopathy, which is a condition that can cause significant impairments in physical functioning.
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Kevin P. Weinfurt, PhD, Department of Population Health Sciences, Duke University School of Medicine, 215 Morris St, Durham, NC 27701 (email@example.com).
Published Online: July 15, 2022. doi:10.1001/jama.2022.11238
Conflict of Interest Disclosures: Dr Weinfurt reported receiving personal fees from Regeneron Pharmaceuticals and being a co-developer of the National Institutes of Health–funded Patient-Reported Outcomes Measurement Information System (PROMIS) and the Comprehensive Assessment of Self-Reported Urinary Symptoms. Dr Reeve reported receiving personal fees from Johns Hopkins University; receiving nonfinancial support from the European Organisation for Research and Treatment of Cancer; and being a co-developer of PROMIS, the Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events, the Observer-Reported Communication Ability, the Piper Fatigue Scale-12, the Patient-Centered Communication in Cancer Care, the Comprehensive Heart Disease Knowledge Questionnaire, the 2005 Healthy Eating Index, and the Everyday Discrimination Scale.
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