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Contraception in Women With Cardiovascular Disease

To identify the key insights or developments described in this article
1 Credit CME

An increasing population of women of childbearing age have underlying congenital or acquired cardiovascular disease (CVD) in the US.1,2 For instance, among women aged 20 to 29 years, the prevalence of CVD (eg, coronary heart disease, heart failure, stroke, and hypertension) is estimated at 11.5%.3 The reasons for this include improved pediatric cardiac surgical care, which has enabled more than 90% of children with congenital heart disease to survive to adulthood, and increasing rates of cardiovascular (CV) risk factors among young women (eg, obesity, hypertension, and diabetes).2

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Stephanie B. Teal, MD, MPH, Department of Obstetrics and Gynecology and Reproductive Biology, University Hospitals Cleveland Medical Center, 11100 Euclid St, MAC-5034, Cleveland, OH 44106 (stephanie.teal@uhhospitals.org).

Published Online: July 22, 2022. doi:10.1001/jama.2022.11541

Conflict of Interest Disclosures: Dr Teal reported honoraria from Merck & Co (data and safety monitoring board) and Bayer Healthcare (scientific advisory board); and grants to her institution while serving as principal investigator from Merck & Co, Bayer Healthcare, Sebela, Medicines 360, and Chemo Research outside the submitted work. No other disclosures were reported.

References
1.
Lindley  KJ , Bairey Merz  CN , Davis  MB ,  et al.  Contraception and reproductive planning for women with cardiovascular disease.   J Am Coll Cardiol. 2021;77(14):1823-1834.PubMedGoogle ScholarCrossref
2.
Lindley  KJ , Bairey Merz  CN , Asgar  AW ,  et al.  Management of women with congenital or inherited cardiovascular disease from pre-conception through pregnancy and postpartum.   J Am Coll Cardiol. 2021;77(14):1778-1798.PubMedGoogle ScholarCrossref
3.
Benjamin  EJ , Virani  SS , Callaway  CW ,  et al.  Heart disease and stroke statistics - 2018 update.   Circulation. 2018;137(12):e67-e492. PubMedGoogle ScholarCrossref
4.
Davis  MB , Arendt  K , Bello  NA ,  et al.  Team-based care of women with cardiovascular disease from pre-conception through pregnancy and postpartum.   J Am Coll Cardiol. 2021;77(14):1763-1777.PubMedGoogle ScholarCrossref
5.
 ACOG Practice Bulletin No. 206 Summary: use of hormonal contraception in women with coexisting medical conditions.   Obstet Gynecol. 2019;133(2):396-399. doi:10.1097/AOG.0000000000003073PubMedGoogle ScholarCrossref
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Kavanaugh  ML , Pliskin  E .  Use of contraception among reproductive-aged women in the United States, 2014 and 2016.   F S Rep. 2020;1(2):83-93. PubMedGoogle Scholar
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Teal  S , Edelman  A.   Contraception selection, effectiveness, and adverse effects.   JAMA. 2021;326(24):2507-2518. doi:10.1001/jama.2021.21392PubMedGoogle ScholarCrossref
8.
Curtis  KM , Tepper  NK , Jatlaoui  TC ,  et al.  US medical eligibility criteria for contraceptive use, 2016.   MMWR Recomm Rep. 2016;65(3):1-103.PubMedGoogle ScholarCrossref
9.
Tepper  NK , Whiteman  MK , Marchbanks  PA , James  AH , Curtis  KM .  Progestin-only contraception and thromboembolism.   Contraception 2016;94(6):678-700. doi:10.1016/j.contraception.2016.04.014PubMedGoogle ScholarCrossref
10.
Castillo  K , Zambrano  K , Barba  D ,  et al  Long-acting reversible contraceptives effects in abnormal uterine bleeding.   Eur J Obstet Gynecol Reprod Biol. 2022;270:231-238. doi:10.1016/j.ejogrb.2022.01.020PubMedGoogle ScholarCrossref
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