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Monkeypox Infection

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A man in his 30s presented to the emergency department with a 1-week history of mucopurulent anal discharge and tenesmus, as well as a 2-day history of pruritic perianal lesions. Physical examination revealed multiple subcentimeter vesicles and papulovesicules with central necrosis surrounding the anal opening (Figure). The patient did not have a fever and had no systemic symptoms. Palpable lymphadenopathy was present in the inguinal basin. The patient had traveled to Gran Canaria (Spain) the week before symptom onset, and he reported an unprotected sexual encounter with another man 5 days before symptom onset.

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Article Information

Corresponding Author: Rafael Escudero-Tornero, MD, Servicio de Dermatología, Hospital Universitario La Paz, Paseo de la Castellana, 261, Madrid 28046, Spain (rafaelescuderotornero@gmail.com).

Published Online: August 25, 2022. doi:10.1001/jamadermatol.2022.3975

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

References
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Adler  H , Gould  S , Hine  P ,  et al; NHS England High Consequence Infectious Diseases (Airborne) Network.  Clinical features and management of human monkeypox: a retrospective observational study in the UK.   Lancet Infect Dis. 2022;22(8):1153-1162. doi:10.1016/S1473-3099(22)00228-6PubMedGoogle ScholarCrossref
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Antinori  A , Mazzotta  V , Vita  S ,  et al; INMI Monkeypox Group.  Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022.   Euro Surveill. 2022;27(22):1-6. doi:10.2807/1560-7917.ES.2022.27.22.2200421PubMedGoogle ScholarCrossref
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World Health Organization. Clinical management and infection prevention and control for monkeypox: interim rapid response guidance. Accessed July 5, 2022. https://www.who.int/publications/i/item/WHO-MPX-Clinical-and-IPC-2022.1
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