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Dermatology

Monkeypox Infection

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1 Credit CME

JAMA Dermatology

Published Online: August 25, 2022

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Article Information and Disclosures

Rafael Escudero-Tornero, MD¹;

Tristán-Gabriel Sobral-Costas, MD¹;

Guillermo Servera-Negre, MD¹

Author Affiliations

¹Department of Dermatology, La Paz University Hospital, Madrid, Spain

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A man in his 30s presented to the emergency department with a 1-week history of mucopurulent anal discharge and tenesmus, as well as a 2-day history of pruritic perianal lesions. Physical examination revealed multiple subcentimeter vesicles and papulovesicules with central necrosis surrounding the anal opening (Figure). The patient did not have a fever and had no systemic symptoms. Palpable lymphadenopathy was present in the inguinal basin. The patient had traveled to Gran Canaria (Spain) the week before symptom onset, and he reported an unprotected sexual encounter with another man 5 days before symptom onset.

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Article Information

Corresponding Author: Rafael Escudero-Tornero, MD, Servicio de Dermatología, Hospital Universitario La Paz, Paseo de la Castellana, 261, Madrid 28046, Spain (rafaelescuderotornero@gmail.com).

Published Online: August 25, 2022. doi:10.1001/jamadermatol.2022.3975

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

References

Petersen E , Kantele A , Koopmans M , et al. Human monkeypox: epidemiologic and clinical characteristics, diagnosis, and prevention. Infect Dis Clin North Am. 2019;33(4):1027-1043. doi:10.1016/j.idc.2019.03.001 PubMed Google Scholar Crossref

Adler H , Gould S , Hine P , et al; NHS England High Consequence Infectious Diseases (Airborne) Network. Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis. 2022;22(8):1153-1162. doi:10.1016/S1473-3099(22)00228-6 PubMed Google Scholar Crossref

Antinori A , Mazzotta V , Vita S , et al; INMI Monkeypox Group. Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Euro Surveill. 2022;27(22):1-6. doi:10.2807/1560-7917.ES.2022.27.22.2200421 PubMed Google Scholar Crossref

World Health Organization. Clinical management and infection prevention and control for monkeypox: interim rapid response guidance. Accessed July 5, 2022. https://www.who.int/publications/i/item/WHO-MPX-Clinical-and-IPC-2022.1

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.