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Neurogenic Unilateral Leg Edema

To identify the key insights or developments described in this article
1 Credit CME

Unilateral leg edema is almost always caused by a disease process that obstructs the venous or lymphatic drainage in the leg or pelvis but can also occur in chronic regional pain syndrome (CRPS).1 We report unilateral leg edema that was a consequence of CRPS induced by an S1 radiculopathy (type 2 CRPS). We show that the etiology of the edema was neurogenic because a posterior tibial nerve block abolished the edema distal to the block.

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Article Information

Corresponding Author: Howard Feit, MD, PhD, Henry Ford Hospital, 6358 Timberwood S, West Bloomfield, MI 48322 (feit.howard@gmail.com).

Published Online: September 26, 2022. doi:10.1001/jamaneurol.2022.2933

Conflict of Interest Disclosures: None reported.

References
1.
Harden  NR , Bruehl  S , Perez  RSGM ,  et al.  Validation of proposed diagnostic criteria (the “Budapest criteria”) for complex regional pain syndrome.   Pain. 2010;150(2):268-274. doi:10.1016/j.pain.2010.04.030PubMedGoogle ScholarCrossref
2.
Howarth  D , Burstal  R , Hayes  C , Lan  L , Lantry  G .  Autonomic regulation of lymphatic flow in the lower extremity demonstrated on lymphoscintigraphy in patients with reflex sympathetic dystrophy.   Clin Nucl Med. 1999;24(6):383-387. doi:10.1097/00003072-199906000-00001PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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