Corresponding Author: Brendan Lee, MD, PhD, Baylor College of Medicine, One Baylor Plaza, ABBR-R814, Houston, TX 77030 (blee@bcm.edu).
Published Online: December 16, 2022. doi:10.1001/jama.2022.22843
Conflict of Interest Disclosures: The authors are employees of Baylor College of Medicine, which is co-owner of Baylor Genetics, a diagnostic genetic testing company. The authors did not receive any personal compensation from Baylor Genetics.
Funding/Support: This work was supported by grants from the National Institutes of Health (U01 HG007709 to Dr Lee, T32 GM007526 to Dr Ketkar, and U54 OD030165 to Dr Burrage). Dr Burrage is also supported by a Career Award for Medical Scientists from the Burroughs Wellcome Fund.
Role of the Funder/Sponsor: The funders had no role in the preparation, review, or approval of the manuscript, or the decision to submit the manuscript for publication.