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Pigmented Corneal Lesions After Cataract Surgery

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

An 81-year-old woman was referred to our service for assessment of 3 darkly pigmented corneal lesions (Figure 1A). Two years ago, she underwent uncomplicated right cataract surgery at a different center. Her postoperative course had been complicated by persistent low-grade anterior uveitis for which she received maintenance loteprednol, 0.5%, eye drops on alternate days. She also used latanoprost eye drops at night in both eyes for primary open-angle glaucoma. Her medical history was only significant for hypertension, which was well controlled with ramipril. She denied any ocular trauma or recent travel outside of the country. Review of systems was unremarkable.

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An 81-year-old woman was referred to our service for assessment of 3 darkly pigmented corneal lesions (Figure 1A). Two years ago, she underwent uncomplicated right cataract surgery at a different center. Her postoperative course had been complicated by persistent low-grade anterior uveitis for which she received maintenance loteprednol, 0.5%, eye drops on alternate days. She also used latanoprost eye drops at night in both eyes for primary open-angle glaucoma. Her medical history was only significant for hypertension, which was well controlled with ramipril. She denied any ocular trauma or recent travel outside of the country. Review of systems was unremarkable.

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Article Information

Corresponding Author: Sarah Schimansky, MB, BCh, BAO, Bristol Eye Hospital, University Hospitals Bristol, Weston NHS Foundation Trust, Lower Maudlin Street, Bristol BS1 2LX, United Kingdom (sarah.schimansky@nhs.net).

Published Online: February 9, 2023. doi:10.1001/jamaophthalmol.2022.6308

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

References
1.
Rai  M , Ingle  AP , Ingle  P ,  et al.  Recent advances on mycotic keratitis caused by dematiaceous hyphomycetes.   J Appl Microbiol. 2021;131(4):1652-1667. doi:10.1111/jam.15008 PubMedGoogle ScholarCrossref
2.
Mills  B , Radhakrishnan  N , Karthikeyan Rajapandian  SG , Rameshkumar  G , Lalitha  P , Prajna  NV .  The role of fungi in fungal keratitis.   Exp Eye Res. 2021;202:108372. doi:10.1016/j.exer.2020.108372 PubMedGoogle ScholarCrossref
3.
Prajna  NV , Krishnan  T , Mascarenhas  J ,  et al.  Predictors of outcome in fungal keratitis.   Eye (Lond). 2012;26(9):1226-1231. doi:10.1038/eye.2012.99 PubMedGoogle ScholarCrossref
4.
Brown  L , Leck  AK , Gichangi  M , Burton  MJ , Denning  DW .  The global incidence and diagnosis of fungal keratitis.   Lancet Infect Dis. 2021;21(3):e49-e57. doi:10.1016/S1473-3099(20)30448-5 PubMedGoogle ScholarCrossref
5.
Mahmoudi  S , Masoomi  A , Ahmadikia  K ,  et al.  Fungal keratitis: an overview of clinical and laboratory aspects.   Mycoses. 2018;61(12):916-930. doi:10.1111/myc.12822 PubMedGoogle ScholarCrossref
6.
Knutsson  KA , Iovieno  A , Matuska  S , Fontana  L , Rama  P .  Topical corticosteroids and fungal keratitis: a review of the literature and case series.   J Clin Med. 2021;10(6):1178. doi:10.3390/jcm10061178 PubMedGoogle ScholarCrossref
7.
Maharana  PK , Sharma  N , Nagpal  R , Jhanji  V , Das  S , Vajpayee  RB .  Recent advances in diagnosis and management of mycotic keratitis.   Indian J Ophthalmol. 2016;64(5):346-357. doi:10.4103/0301-4738.185592 PubMedGoogle ScholarCrossref
8.
Wykoff  CC , Flynn  HW  Jr , Miller  D , Scott  IU , Alfonso  EC .  Exogenous fungal endophthalmitis: microbiology and clinical outcomes.   Ophthalmology. 2008;115(9):1501-1507, 1507.e1-1507.e2. doi:10.1016/j.ophtha.2008.02.027PubMedGoogle ScholarCrossref
9.
Romaniuk  W , Koziol  H , Muskalski  K , Dorecka  M , Tarnawska  D , Sabat  D .  A unique case of primary corneal melanoma.   Jpn J Ophthalmol. 2002;46(1):114-116. doi:10.1016/S0021-5155(01)00462-2 PubMedGoogle ScholarCrossref
10.
Uçakhan-Gündüz  Ö , Gündüz  K , Karsloğlu  MZ , Okçu-Heper  A , Kanpolat  A .  Corneal melanoma: report of three cases.   Eye Contact Lens. 2012;38(5):341-344. doi:10.1097/ICL.0b013e318237d195 PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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