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Silicone Oil Droplet Over the Optic Nerve Head After Intravitreal Injections

To identify the key insights or developments described in this article
1 Credit CME

A nearly 80-year-old patient presented with branch retinal vein occlusion of the left eye and cystoid macular edema, without evidence of capillary nonperfusion. At the baseline visit, their visual acuity was 6/6 (20/20) OD and 6/18 (20/63) OS. Over a 6-year period, the patient received the following interventions: 9 bevacizumab injections, 1 triamcinolone injection, and 7 dexamethasone intraocular implants. During a routine follow-up visit, the patient was noted to have a silicone oil droplet over the optic nerve head (Figure, A and B). This was asymptomatic and required no treatment.

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Article Information

Corresponding Author: Thomas Weatherby, MA, MB, BChir, Aintree University Hospital, Liverpool L9 7AL, United Kingdom (tom.weatherby@aintree.nhs.uk).

Conflict of Interest Disclosures: None reported.

References
1.
Bakri  SJ , Ekdawi  NS .  Intravitreal silicone oil droplets after intravitreal drug injections.   Retina. 2008;28(7):996-1001. doi:10.1097/IAE.0b013e31816c6868PubMedGoogle ScholarCrossref
2.
Avery  RL , Castellarin  AA , Dhoot  DS ,  et al.  Large silicone droplets after intravitreal bevacizumab (Avastin).   Retin Cases Brief Rep. 2019;13(2):130-134. doi:10.1097/ICB.0000000000000570PubMedGoogle ScholarCrossref
3.
Melo  GB , Dias Junior  CS , Carvalho  MR ,  et al.  Release of silicone oil droplets from syringes.   Int J Retina Vitreous. 2019;5:1. doi:10.1186/s40942-018-0153-8PubMedGoogle ScholarCrossref
4.
Olea  JL , Gómez-Resa  M , Cervera-Peris  MM , Aragón  JA .  Silicone oil droplets in repackaged antivascular endothelial growth factors for intravitreal injections: in search of the main source of contamination.   Eur J Ophthalmol. 2020;30(4):774-779.PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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