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Noninvasive Blue-Light Channel Imaging of Retinal Nonperfusion in Vein Occlusion

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1 Credit CME

A patient was diagnosed with nonperfused, inferior, hemiretinal vein occlusion but could not undergo fluorescein angiography examination due to a positive history of fluorescein allergy. Thus, the patient’s retinal imaging was assessed by deconstructing the single truecolor, or RGB, image into color channels: the blue channel (BC; 435-500 nm; highlights the anterior retinal layers), green channel (500-585 nm; scans the sensory retina to the retinal pigment epithelium [RPE]), and the red channel (585-640 nm; delineates the deeper structures from the RPE to the choroid) (Figure).1,2 The BC allowed the visualization of the capillary nonperfused areas that appear as dark patches in contrast to the grayish appearance of the perfused retina. The focal brightness along the nasal vessel (pink arrowhead) corresponds to a flame-shaped hemorrhage. This is a noninvasive procedure with no reports of photic injuries.3 The patient’s treatment was conducted based on the images obtained, which provided a noninvasive alternative to fluorescein angiography to identify nonperfused areas of the retina.

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Article Information

Corresponding Author: Gabriel Castilho Sandoval Barbosa, MD, Department of Ophthalmology, Suel Abujamra Institute, Tamandaré Street, No. 655, Apt 106, São Paulo 01525-001, Brazil (gabrielcastilho.oftalmo@gmail.com).

Conflict of Interest Disclosures: None reported.

References
1.
PatentScope. Systems and methods for broad line fundus imaging. Accessed November 18, 2021. https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2014140256&tab=PCTDESCRIPTION
2.
Carl Zeiss Meditec Inc. Zeiss Clarus 500 introduces broad line fundus imaging for fundus autofluorescence. Accessed November 18, 2021. https://www.zeiss.com/content/dam/z/med/reference-master/product-portfolio/retinal-cameras/clarus-700/downloads/clarus_white_paper_final_en_31_025_0268i_cam9724.pdf
3.
Mainster  MA , Turner  PL .  Retinal examination and photography are safe...is anyone surprised?   Ophthalmology. 2010;117(2):197-198. doi:10.1016/j.ophtha.2009.11.046PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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