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A Young Woman With Dyspnea During Cardiac Catheterization

Educational Objective
Based on this clinical scenario and the accompanying image, understand how to arrive at a correct diagnosis.
1 Credit CME

A woman in her mid-20s was evaluated for a history of dyspnea on exertion for 2 years. On physical examination, her pulse was 70 beats per minute, and blood pressure was 110/70 mm Hg. The cardiovascular examination showed a loud S1, normal S2, and an opening snap along with a mid-diastolic, soft, rumbling murmur at the apex of the heart. The electrocardiogram showed normal sinus rhythm with left atrial enlargement. The echocardiogram showed severe mitral stenosis with a mitral valve area of 0.9 cm2 with a mean (SD) gradient of 20 (4) mm Hg. There was no evidence of any subvalvular thickening, leaflet calcification, or mitral regurgitation. The patient was taken for balloon mitral valvotomy (BMV). A 6F pigtail catheter was placed in the left ventricle via the right femoral artery. The interatrial septum was punctured using a Mullins sheath and Brockenbrough needle via the right femoral vein. Entry into the left atrium was made and confirmed with a dye injection. However, suddenly, the patient developed acute onset of dyspnea along with retrosternal chest pain. Her blood pressure at the time of the event was 100/60 mm Hg, pulse was 70 beats per minute, and oxygen saturation was 96%. The catheter was pulled back into the right atrium, and chest fluoroscopy was performed (Figure; Video).

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Air embolism in main pulmonary

D. 100% Oxygen, intravenous fluid, and Trendelenburg position

The fluoroscopy of the patient at the onset of dyspnea showed a pulsatile translucency in the main pulmonary artery (MPA). The shape of the opacity was similar to the trunk of the MPA and showed alternating expansion and contraction during the cardiac cycle. The opening and closing of the pulmonary valve were visible at the inferior part of the translucent shadow (Figure; Video). This was diagnosed as a large pulmonary artery air embolism in the MPA.

Pericardial effusion leading to pericardial tamponade is a rare complication of BMV. However, acute tamponade is accompanied by hypotension. Also, on fluoroscopy, tamponade will appear as a decreased movement of cardiac borders along with separation of visceral and parietal pericardium due to accumulation of blood, which was not present in this case. Hence, pericardiocentesis was not indicated. Acute massive pulmonary thromboembolism in the MPA gives rise to acute-onset hypotension and dyspnea, but fluoroscopy is usually unremarkable. Rarely, fluoroscopy may show a prominent pulmonary artery, an enlarged right descending pulmonary artery (Palla sign), an abrupt cutoff of vessels, elevated hemidiaphragm along with focal pulmonary oligemia (Westermark sign), and peripheral, pleural-based, wedge-shaped opacity (Hampton hump) due to pulmonary infarction. Acute pulmonary embolism appears as a filling defect on contrast angiography rather than on fluoroscopy. As none of these features was present, intravenous thrombolytic and catheter-directed embolectomy were not indicated in this patient.

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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Praveen Gupta, DM, Department of Cardiology, Praveen Heart Clinic and Research Foundation, Nirman Vihar, New Delhi 110092, India (praveenkumargupta2002@gmail.com).

Published Online: March 1, 2023. doi:10.1001/jamacardio.2023.0013

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient for granting permission to publish this information.

References
1.
Ganesan  V , Chirammal Valappil  U , Sebastian  P , Mannambeth Karikkan  A .  Pulmonary artery air embolism after permanent pacemaker implantation.   BMJ Case Rep. 2022;15(5):e249673. doi:10.1136/bcr-2022-249673PubMedGoogle ScholarCrossref
2.
Shaikh  N , Ummunisa  F .  Acute management of vascular air embolism.   J Emerg Trauma Shock. 2009;2(3):180-185. doi:10.4103/0974-2700.55330PubMedGoogle ScholarCrossref
3.
Garg  N , Moorthy  N , Goel  PK .  Intracardiac aspiration for life-threatening air embolism during cardiac catheterization in tetralogy of Fallot: an aborted sudden death.   J Invasive Cardiol. 2012;24(11):E294-E296.PubMedGoogle Scholar
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 CME points in the American Board of Surgery’s (ABS) Continuing Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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