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Perforation During Gynecological Procedures

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1 Credit CME

Uterine perforation is a surgical complication that can occur with any intrauterine procedure. While most perforations can be managed without additional interventions and are not related to important morbidity, uterine perforations can be serious, leading to sepsis, hemorrhage, poor reproductive and obstetric outcomes, and even death.

Preventive strategies for uterine perforation include careful preoperative evaluation, use of appropriate instrumentation and techniques intraoperatively, and adequate training and experience of the surgeon. Preoperatively, preparation includes imaging to assess uterine anatomy and identifying any potential risk factors; consideration for cervical preparation with prostaglandins or osmotic dilators1; and consideration for treatment of any existing vaginal atrophy. However, complications are inevitable for surgeons with high surgical volume and the expertise lies in prompt evaluation, recognition, and management of complications.2 The presurgical consent process should include the possibility of uterine perforation and any additional procedures including laparoscopy or laparotomy. Most perforations occur at the beginning of the procedure with the insertion of cervical dilators, hysteroscope, or sharp instruments with excessive force in a suboptimal axis. Techniques to reduce the incidence of perforation include a bimanual examination prior to dilation, placement of a tenaculum on the cervix to straighten the cervical canal, use of specialized instruments to identify and dilate the cervical canal (eg, os finder, lacrimal duct dilators), use of ultrasound to aid with difficult endometrial access, and proper use of energized instruments (eg, resectoscopic loop movements toward the operator and not the uterine wall).

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Article Information

Corresponding Author: Tommaso Falcone, MD, OBGYN & Women’s Health Institute, 9500 Euclid Ave, Desk A81, Cleveland Clinic, Cleveland, OH 44195 (falcont@ccf.org).

Published Online: March 3, 2023. doi:10.1001/jama.2023.0687

Conflict of Interest Disclosures: None reported.

References
1.
De Silva  PM , Wilson  L , Carnegy  A , Smith  PP , Clark  TJ .  Cervical dilatation and preparation prior to outpatient hysteroscopy: a systematic review and meta-analysis.   BJOG. 2021;128(7):1112-1123. doi:10.1111/1471-0528.16604PubMedGoogle ScholarCrossref
2.
Shveiky  D , Rojansky  N , Revel  A , Benshushan  A , Laufer  N , Shushan  A .  Complications of hysteroscopic surgery: “beyond the learning curve”.   J Minim Invasive Gynecol. 2007;14(2):218-222. doi:10.1016/j.jmig.2006.07.019PubMedGoogle ScholarCrossref
3.
Reed  SD , Zhou  X , Ichikawa  L ,  et al; APEX-IUD study team.  Intrauterine device-related uterine perforation incidence and risk (APEX-IUD): a large multisite cohort study.   Lancet. 2022;399(10341):2103-2112. doi:10.1016/S0140-6736(22)00015-0PubMedGoogle ScholarCrossref
4.
Jansen  FW , Vredevoogd  CB , van Ulzen  K , Hermans  J , Trimbos  JB , Trimbos-Kemper  TC .  Complications of hysteroscopy: a prospective, multicenter study.   Obstet Gynecol. 2000;96(2):266-270. doi:10.1097/00006250-200008000-00021PubMedGoogle ScholarCrossref
5.
Agostini  A , Cravello  L , Bretelle  F , Shojai  R , Roger  V , Blanc  B .  Risk of uterine perforation during hysteroscopic surgery.   J Am Assoc Gynecol Laparosc. 2002;9(3):264-267. doi:10.1016/S1074-3804(05)60401-XPubMedGoogle ScholarCrossref
6.
Shu  M , Nassar  D , Chun  CY , Griffin  A .  Intrauterine fallopian tube incarceration after suction curettage with uterine perforation.   J Minim Invasive Gynecol. 2022;29(4):457-459. doi:10.1016/j.jmig.2021.12.006PubMedGoogle ScholarCrossref
7.
Sentilhes  L , Sergent  F , Berthier  A , Catala  L , Descamps  P , Marpeau  L .  Uterine rupture following operative hysteroscopy [in French].   Gynecol Obstet Fertil. 2006;34(11):1064-1070. doi:10.1016/j.gyobfe.2006.09.004PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

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