A middle-aged woman was admitted to the hospital due to syncope. According to results of the auscultation, the woman was initially diagnosed as having mitral stenosis after detection of a mid-diastolic, low-pitched, rumbling murmur and an audible opening snap at the apex. The patient also exhibited malar flush, which is a common skin manifestation in patients with mitral stenosis1; this finding further supported our diagnosis (Figure, A). However, an echogenic mass, measuring 32 × 28 mm (Figure, B), was detected in the left atrium by transthoracic echocardiography. The mass was connected to the intertribal septum via a short flap, prolapsing across the mitral valve into the left ventricle and causing transient obstruction of blood flow (Video). The opening snap and diastolic murmur were actually the result of movement of the myxomatous tumor and obstruction of the valve, respectively.2 The patient was then referred for surgical resection. Pathology confirmed a diagnosis of myxoma.
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Published Online: April 26, 2023. doi:10.1001/jamacardio.2023.0727
Corresponding Authors: Yanmei Lu, MD, PhD (email@example.com), and Baopeng Tang, MD, PhD (firstname.lastname@example.org), Department of Cardiac Pacing and Electrophysiology, The First Affiliated Hospital of Xinjiang Medical University, No. 137, South Liyushan Road, Xinshi Zone, Urumqi 830054, China.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was funded in part by grants 81660071, 81860081 from the National Natural Science Foundation and grant 2022TSYCCX0101 from Provincial Top Young Scientific and Technological Talents of Tianshan Talent Cultivation Program.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: We thank the patient for granting permission to publish this information.
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