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Cardiology

Extracorporeal Cardiopulmonary Resuscitation for Cardiac Arrest

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JAMA

Published Online: April 27, 2023

JAMA Insights

Article Information and Disclosures

Asger Granfeldt, MD, PhD, DMSc^1,2;

Mathias J. Holmberg, MD, PhD, MPH¹;

Lars W. Andersen, MD, MPH, PhD, DMSc^1,2,3

Author Affiliations

¹Department of Clinical Medicine, Aarhus University, Denmark
²Department of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark
³Prehospital Emergency Medical Services, Central Denmark Region, Aarhus, Denmark

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Article Information

Accepted for Publication: March 21, 2023.

Published Online: April 27, 2023. doi:10.1001/jama.2023.5585

Corresponding Author: Lars W. Andersen, MD, MPH, PhD, DMSc, Department of Anesthesiology and Intensive Care, Aarhus University Hospital, Denmark (lwandersen@clin.au.dk).

Conflict of Interest Disclosures: Dr Granfeldt reported receiving personal fees for serving on a data and safety monitoring board for Noorik Pharmaceuticals and being a consultant for NMD Pharma outside the submitted work. No other disclosures were reported.

Disclaimer: Dr Andersen is a statistical reviewer for JAMA but was not involved in any of the decisions regarding review of the manuscript or its acceptance.

References

Andersen LW , Holmberg MJ , Berg KM , Donnino MW , Granfeldt A . In-hospital cardiac arrest: a review. JAMA. 2019;321(12):1200-1210.PubMed Google Scholar Crossref

Belohlavek J , Smalcova J , Rob D , et al. Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment and treatment on functional neurologic outcome in refractory out-of-hospital cardiac arrest. JAMA. 2022;327(8):737-747.PubMed Google Scholar Crossref

Richardson ASC , Tonna JE , Nanjayya V , et al. Extracorporeal cardiopulmonary resuscitation in adults. ASAIO J. 2021;67(3):221-228.PubMed Google Scholar Crossref

Extracorporeal Life Support Organization. ECLS registry report. October 2021. Accessed April 14, 2023. https://www.elso.org/portals/0/files/reports/2021_october/international%20report%20october_page1.pdf

Yannopoulos D , Bartos J , Raveendran G , et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST). Lancet. 2020;396(10265):1807-1816.PubMed Google Scholar Crossref

Suverein MM , Delnoij TSR , Lorusso R , et al. Early extracorporeal CPR for refractory out-of-hospital cardiac arrest. N Engl J Med. 2023;388(4):299-309.PubMed Google Scholar Crossref

Holmberg MJ , Granfeldt A , Guerguerian AM , et al. Extracorporeal cardiopulmonary resuscitation for cardiac arrest. Resuscitation. 2023;182:109665.PubMed Google Scholar

International Liaison Committee on Resuscitation Advanced Life Support Task Force. Extracorporeal Cardiopulmonary Resuscitation (ECPR) for Cardiac Arrest. Consensus on Science With Treatment Recommendations; 2022. Accessed April 14, 2023. https://costr.ilcor.org/document/extracorporeal-cardiopulmonary-resuscitation-ecpr-for-cardiac-arrest-als-tfsr

Bertic M , Worme M , Foroutan F , et al. Predictors of survival and favorable neurologic outcome in patients treated with eCPR. J Cardiovasc Transl Res. 2022;15(2):279-290.PubMed Google Scholar Crossref

Gottula AL , Shaw CR , Gorder KL , et al. Eligibility of out-of-hospital cardiac arrest patients for extracorporeal cardiopulmonary resuscitation in the United States. Resuscitation. 2022;180:111-120.PubMed Google Scholar Crossref

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.