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Infectious Diseases

Outbreak of Cosmetology-Acquired Mycobacterium abscessus Skin Infection

To identify the key insights or developments described in this article

1 Credit CME

JAMA Dermatology

Published Online: May 3, 2023

Images in Dermatology

Article Information and Disclosures

Yuansu Jiang, MM¹;

Weiping Lu, MD¹

Author Affiliations

¹Department of Clinical Laboratory, Daping Hospital of Army Medical University, Chongqing, China
²Department of Dermatology, Daping Hospital of Army Medical University, Chongqing, China

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Six patients presented to the dermatology department due to skin abscess of 1 month’s duration. They all underwent a catgut implant procedure at acupoint for treatment of obesity with materials made by the same manufacturer. The patients were treated with β-lactam antibiotics without improvement. Physical examination of multiple patients revealed numerous warm, red, edematous, tender, fluctuant, and purulent draining nodules on the abdomen (Figure, A). Microscopic examination revealed gram-positive bacilli with positive acid-fast staining and elongated branching morphology identified as Mycobacterium abscessus (M abscessus) by matrix-assisted laser desorption/ionization time of flight mass spectrometry (Figure, B).

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Article Information

Corresponding Author: Weiping Lu, MD, Department of Clinical Laboratory, Daping Hospital of Army Medical University, No. 10 Changjiang Branch Rd, Daping, Yuzhong District, Chongqing 400042, China (luweiping19710416@163.com).

Published Online: May 3, 2023. doi:10.1001/jamadermatol.2022.6385

Conflict of Interest Disclosures: None reported.

Additional Contributions: We thank the patient whose clinical images are depicted in the Figure for granting permission to publish this information.

References

Wang X , Wan M , Zhang L , et al. ALA_PDT promotes ferroptosis-like death of Mycobacterium abscessus and antibiotic sterilization via oxidative stress. Antioxidants (Basel). 2022;11(3):546. doi:10.3390/antiox11030546 PubMed Google Scholar Crossref

Li H , Mulati G , Shang Y , et al. Rapid detection of clarithromycin and amikacin resistance in Mycobacterium abscessus complex by high-resolution melting curve analysis. Microbiol Spectr. 2022;10(3):e0057422. doi:10.1128/spectrum.00574-22 PubMed Google Scholar Crossref

Johansen MD , Herrmann JL , Kremer L . Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus. Nat Rev Microbiol. 2020;18(7):392-407. doi:10.1038/s41579-020-0331-1 PubMed Google Scholar Crossref

Dedrick RM , Guerrero-Bustamante CA , Garlena RA , et al. Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus. Nat Med. 2019;25(5):730-733. doi:10.1038/s41591-019-0437-z PubMed Google Scholar Crossref

AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.