[Skip to Content]
[Skip to Content Landing]

ST-Segment Elevation Followed by de Winter Electrocardiogram Pattern in a Patient With Chest Pain

To identify the key insights or developments described in this article
1 Credit CME

A patient in their 40s with no history of cardiovascular disease presented to the emergency department with a constant, substernal chest pain accompanied by sweating, which had started one and a half hours prior.

On arrival, the patient’s vital signs were as follows: blood pressure, 158/77 mm Hg; pulse, 78 beats/min; temperature, 36.0 °C; respiratory rate, 16 breaths/min; and oxygen saturation was 95% on room air. The patient was hemodynamically stable, and physical examination findings were unremarkable. Results of blood chemistry tests and complete blood cell count were within normal limits. The result of an initial troponin I test was normal. An electrocardiogram (ECG) was obtained (Figure, A). Forty minutes later, a preoperative ECG was performed (Figure, B).

Please finish quiz first before checking answer.

You answered correctly!

Read the answer below and download your certificate.

You answered incorrectly.

Read the discussion below and retake the quiz.

A patient in their 40s with no history of cardiovascular disease presented to the emergency department with a constant, substernal chest pain accompanied by sweating, which had started one and a half hours prior.

On arrival, the patient’s vital signs were as follows: blood pressure, 158/77 mm Hg; pulse, 78 beats/min; temperature, 36.0 °C; respiratory rate, 16 breaths/min; and oxygen saturation was 95% on room air. The patient was hemodynamically stable, and physical examination findings were unremarkable. Results of blood chemistry tests and complete blood cell count were within normal limits. The result of an initial troponin I test was normal. An electrocardiogram (ECG) was obtained (Figure, A). Forty minutes later, a preoperative ECG was performed (Figure, B).

Survey Complete!

Sign in to take quiz and track your certificates

Buy This Activity

JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 Credit(s)™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC

CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.

Article Information

Corresponding Author: Yongxia Wu, MD, Division of Cardiology, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing 101149, China (13699106575@139.com).

Published Online: June 20, 2023. doi:10.1001/jamainternmed.2023.1558

Conflict of Interest Disclosures: None reported.

References
1.
Verouden  NJ , Koch  KT , Peters  RJ ,  et al.  Persistent precordial “hyperacute” T-waves signify proximal left anterior descending artery occlusion.   Heart. 2009;95(20):1701-1706. doi:10.1136/hrt.2009.174557PubMedGoogle ScholarCrossref
2.
Morris  NP , Body  R .  The de Winter ECG pattern: morphology and accuracy for diagnosing acute coronary occlusion: systematic review.   Eur J Emerg Med. 2017;24(4):236-242. doi:10.1097/MEJ.0000000000000463PubMedGoogle ScholarCrossref
3.
Karna  S , Chourasiya  M , Chaudhari  T , Bakrenia  S , Patel  U .  De Winter sign in inferior leads: a rare presentation.   Heart Views. 2019;20(1):25-27. doi:10.4103/HEARTVIEWS.HEARTVIEWS_4_19PubMedGoogle ScholarCrossref
4.
Xu  W , Zou  H , Huang  S .  Junctional ST-depression and tall symmetrical T-waves with an obtuse marginal artery occlusion: a case report.   J Electrocardiol. 2019;54:40-42. doi:10.1016/j.jelectrocard.2019.03.006PubMedGoogle ScholarCrossref
5.
de Winter  RJ , Verouden  NJ , Wellens  HJ , Wilde  AA ; Interventional Cardiology Group of the Academic Medical Center.  A new ECG sign of proximal LAD occlusion.   N Engl J Med. 2008;359(19):2071-2073. doi:10.1056/NEJMc0804737PubMedGoogle ScholarCrossref
6.
Fiol Sala  M , Bayés de Luna  A , Carrillo López  A , García-Niebla  J .  The “de Winter pattern” can progress to ST-segment elevation acute coronary syndrome.   Rev Esp Cardiol (Engl Ed). 2015;68(11):1042-1043. doi:10.1016/j.recesp.2015.07.009PubMedGoogle ScholarCrossref
7.
Lam  RPK , Cheung  ACK , Wai  AKC , Wong  RTM , Tse  TS .  The de Winter ECG pattern occurred after ST-segment elevation in a patient with chest pain.   Intern Emerg Med. 2019;14(5):807-809. doi:10.1007/s11739-018-02013-zPubMedGoogle ScholarCrossref
8.
Ayer  A , Terkelsen  CJ .  Difficult ECGs in STEMI: lessons learned from serial sampling of pre- and in-hospital ECGs.   J Electrocardiol. 2014;47(4):448-458. doi:10.1016/j.jelectrocard.2014.03.010PubMedGoogle ScholarCrossref
9.
Huang  W , Mai  L , Lu  J , Li  W , Huang  Y , Hu  Y .  Evolutionary de Winter pattern: from STEMI to de Winter ECG-a case report.   ESC Heart Fail. 2022;9(1):771-774. doi:10.1002/ehf2.13711PubMedGoogle ScholarCrossref
10.
Zhao  YT , Wang  L , Yi  Z .  Evolvement to the de Winter electrocardiographic pattern.   Am J Emerg Med. 2016;34(2):330-332. doi:10.1016/j.ajem.2015.11.057PubMedGoogle ScholarCrossref
AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

  • 1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
  • 1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
  • 1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
  • 1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
  • 1.00 credit toward the CME of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.

Close
Want full access to the AMA Ed Hub?
After you sign up for AMA Membership, make sure you sign in or create a Physician account with the AMA in order to access all learning activities on the AMA Ed Hub
Buy this activity
Close
Want full access to the AMA Ed Hub?
After you sign up for AMA Membership, make sure you sign in or create a Physician account with the AMA in order to access all learning activities on the AMA Ed Hub
Buy this activity
Close
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Education Center Collection Sign In Modal Right
Close

Name Your Search

Save Search
With a personal account, you can:
  • Access free activities and track your credits
  • Personalize content alerts
  • Customize your interests
  • Fully personalize your learning experience
Close
Close

Lookup An Activity

or

My Saved Searches

You currently have no searches saved.

Close

My Saved Courses

You currently have no courses saved.

Close