Pneumocystis jirovecii is an opportunistic fungal pathogen that causes life-threatening pneumonia in immunocompromised patients. Patients with Pneumocystis pneumonia (PCP) typically present with fever, nonproductive cough, dyspnea, and hypoxemia with diffuse bilateral ground-glass opacities on chest imaging.1 PCP can be prevented by reducing immunosuppression and with chemoprophylaxis. Effective prophylaxis significantly decreases the incidence of infection.2 This article summarizes current recommendations regarding prevention of PCP in patients who are immunocompromised.3- 5
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Corresponding Author: Shiwei Zhou, MD, Michigan Medicine, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI 48109 (email@example.com).
Published Online: June 26, 2023. doi:10.1001/jama.2023.9844
Correction: This article was corrected on September 13, 2023, to correct typographical errors in the Table.
Conflict of Interest Disclosures: Dr Aitken reported receiving personal fees from bioMerieux, F2G, Entasis, Shionogi, GSK, Melinta, AstraZeneca, Enstasis, and Basilea outside the submitted work. No other disclosures were reported.
Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:
It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.
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