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Cardiology

Gestational Diabetes and Long-Term Cardiometabolic Health

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JAMA

Published Online: August 10, 2023

JAMA Insights

Article Information and Disclosures

Kartik K. Venkatesh, MD, PhD¹;

Sadiya S. Khan, MD, MSc^2,3;

Camille E. Powe, MD⁴

Author Affiliations

¹Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, The Ohio State University College of Medicine, Columbus
²Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
³Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
⁴Departments of Medicine and Obstetrics, Gynecology, and Reproductive Biology, Diabetes Unit, Massachusetts General Hospital, Harvard Medical School, Boston

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Gestational diabetes mellitus (GDM) (ie, hyperglycemia first diagnosed during pregnancy) is associated with increased risk of adverse perinatal outcomes. GDM is associated with cardiometabolic disease including type 2 diabetes (T2D) and cardiovascular disease (CVD) in the affected pregnant individual and the exposed fetus.¹ In 2020, GDM occurred in nearly 1 in 8 pregnancies in the US, with even higher rates among individuals who identified as American Indian or non-Hispanic Asian/Pacific Islander, those with obesity, and those aged 35 years or older at delivery. The age-standardized rate of GDM at the first live birth has increased from 47.6 to 63.5 per 1000 live births from 2011 to 2019 in the US, with further increases documented during the COVID-19 pandemic.²

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Article Information

Corresponding Author: Kartik K Venkatesh, MD, PhD, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, College of Medicine, The Ohio State University, 395 W 12th Ave, Floor 5, Columbus, OH 43210 (kartik.venkatesh@osumc.edu).

Published Online: August 10, 2023. doi:10.1001/jama.2023.14997

Conflict of Interest Disclosures: Dr Venkatesh reported grant funding from AHRQ, PCORI, and DEXCOM for diabetes in pregnancy research. Dr Khan reported grants from NIH HL161514 outside the submitted work. Dr Powe reported personal fees from Mediflix and Wolters Kluwer/Up To Date outside the submitted work.

References

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AMA CME Accreditation Information

Credit Designation Statement: The American Medical Association designates this Journal-based CME activity activity for a maximum of 1.00  AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to:

1.00 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program;;
1.00 Self-Assessment points in the American Board of Otolaryngology – Head and Neck Surgery’s (ABOHNS) Continuing Certification program;
1.00 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program;
1.00 Lifelong Learning points in the American Board of Pathology’s (ABPath) Continuing Certification program; and
1.00 credit toward the CME [and Self-Assessment requirements] of the American Board of Surgery’s Continuous Certification program

It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting MOC credit.