Bacterial and protozoal sexually transmitted infections (STIs) cause more than 1 million treatable STIs daily worldwide.1 Bacterial STIs can cause significant morbidity. Syphilis can cause meningitis, deafness, blindness, and congenital sequelae, including stillbirth and neonatal death. Chlamydia or gonorrheal infection can cause infertility. Although most bacterial STIs are treatable with accessible and inexpensive antibiotics, challenges to effective STI prevention remain.2,3 Asymptomatic infections are common and may be more prevalent among individuals with low health literacy and among those who have difficulty accessing care and/or avoid medical treatment because of anticipated stigma. STI control programs have traditionally used contact tracing to identify partners of newly diagnosed individuals, but this approach is challenging when individuals meet anonymous partners and public health programs have limited resources.4
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CME Disclosure Statement: Unless noted, all individuals in control of content reported no relevant financial relationships. If applicable, all relevant financial relationships have been mitigated.
Corresponding Author: Kenneth H. Mayer, MD, Fenway Health, 1340 Boylston St, Boston, MA 02215 (email@example.com).
Published Online: September 22, 2023. doi:10.1001/jama.2023.16416
Conflict of Interest Disclosures: Dr Traeger reported receiving grants and personal fees from Gilead Sciences outside the submitted work. No other disclosures were reported.
Funding/Support: This work was supported by the Harvard University Center for AIDS Research (NIAID R24, AI067039).
Role of the Funder/Sponsor: The funder had no role in the design and conduct of the study; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Contributions: The authors wish to recognize the thoughtful comments of Douglas Krakower, MD (Beth Israel Deaconess Medical Center and Harvard Medical School), in reviewing the manuscript and the assistance of Whitney Crebase, MPH (Fenway Health), in the preparation of the manuscript, neither of whom received compensation.
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