Pelvic organ prolapse is an overarching term used to describe the abnormal descent of the vaginal walls and the subsequent herniation of the uterus, uterine cervix, and other pelvic organs to or beyond the hymen.1 Uterine prolapse is a particular form of pelvic organ prolapse that occurs in women with a uterus; it is diagnosed when pelvic organ prolapse affects the top of the vagina.2 Uterine prolapse is a result of the weakening of pelvic floor muscles and connective tissues that support the vagina and is not the result of a problem with the uterus. In many cases of uterine prolapse, the uterus is normal. Even when there is uterine pathology, such as fibroids or abnormal uterine bleeding, uterine pathology does not cause uterine prolapse.
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Corresponding Author: Oluwateniola E. Brown, MD, Northwestern University Feinberg School of Medicine, 250 E Superior, Ste 5-2113, Chicago, IL 60611 (firstname.lastname@example.org).
Published Online: September 25, 2023. doi:10.1001/jama.2023.16277
Conflict of Interest Disclosures: Dr Ackenbom reported grants from the National Institute on Aging, Alzheimer's Association, Pennsylvania Department of Health, and the Tamara Harris Foundation outside the submitted work. No other disclosures were reported.
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