Neurology CME & MOC Cases from JAMA Network

Clinical Challenges in Neurology

Can you correctly diagnose and treat unusual presentations of epilepsy and seizures, cerebrovascular disease, neurodegenerative disease, CNS infections, vasculitis, and more?

Browse the full JN Learning collection of over 250 Neurology CME activities. Take the activities on JN Learning to receive more than 250 CME Credits.

CME 1.0

A Woman With Eosinophilic Brainstem Meningoencephalitis
A previously healthy 25-year-old woman presented with headache, dysarthria, double vision, and dizziness for 1 week.
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CME 1.0

Acute Myelopathy in a Man With Cutaneous Papules
A 46-year-old man presented with acute-onset weakness of his bilateral lower limbs for 3 days, accompanied by ascending numbness to just below his nipples.
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CME 1.0

Multiple Facial Ulcers Following a Stroke
A 66-year-old man presented with multiple progressive ulcers on the right side of his face that had developed over the past 3 months.
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CME 1.0

Facial Numbness, Dysarthria, Muscle Atrophy, and Weakness in a Young Patient
A 19-year-old man presented with 4 years of facial numbness and 3 years of progressive dysarthria and dysphagia.
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CME 1.0

Progressive Ataxia and Downbeat Nystagmus in an Adult
A 63-year-old man presented with progressive unsteadiness, malaise, anorexia, nausea, and vomiting of 1 month’s duration.
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CME 1.0

Sequential Bilateral Vision Loss in a Woman With Scalp Tenderness and Jaw Claudication
A 67-year-old woman with fibromyalgia presented with sequential bilateral vision loss. Vision decreased suddenly in the right eye 3 to 4 weeks prior and in the left eye 5 days prior.
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CME 1.0

Headache, Cognitive Decline, and a Curious Rim-Enhancing Lesion
A 75-year-old man presented with several weeks of intermittent headache that had progressed to severe, persistent headache with right eye pain.
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CME 1.0

A Middle-aged Woman With Severe Scoliosis and Encephalopathy
A 42-year-old woman presented with clinical features of microcephaly, short stature, intellectual disability, severe degree of scoliosis, gait abnormality, and encephalopathy.
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CME 1.0

Neurological Impairments in a Patient Returning From Cuba
A 69-year-old woman returning from a vacation in Cuba was brought to the emergency department directly from the airport.
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CME 1.0

Encephalomyelitis and Lymphadenopathy in a Man in His Early 40s
A white man in his early 40s presented with dizziness and fatigue followed by tingling of both lower extremities as well as gait disturbances.
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