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Effects of Early Goal-Directed Therapy vs Usual Care on In-Hospital Mortality Among Adults With Severe Sepsis in Zambia

Todd Rice, MD, MSc, of Vanderbilt University discusses the rationale for conducting the Simplified Severe Sepsis Protocol 2 (SSSP-2) Trial, which demonstrated an increase in mortality with early goal-directed therapy for sepsis in an emergency department in Zambia. Recorded September 27, 2017. Used with permission.

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