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Critical Care Medicine Video 10 min 46 sec

Conference Presentation: Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Cluster Randomized Trial

JAMA • October 22, 2018

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In this randomized trial, there was no difference in ICU-acquired bloodstream infections caused by multidrug-resistant gram-negative bacteria (MDRGNB) among ventilated ICU patients given chlorhexidine 2% mouthwash, selective oropharyngeal decontamination (mouthpaste with colistin, tobramycin, and nystatin), or selective digestive tract decontamination (the same mouthpaste and gastrointestinal suspension with the same antibiotics), all applied 4 times daily. Bastiaan H. Wittekamp, MD, PhD, of University Medical Center Utrecht, the Netherlands, presents findings from the R-GNOSIS ICU trial at the European Society of Intensive Care Medicine (ESICM) 31st Annual Congress, LIVES 2018, on October 22 in Paris. Used with permission.

Where CME credit is designated, the activity is part of the American Medical Association's accredited CME program. The AMA is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
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