Conference Presentation: Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Cluster Randomized Trial

In this randomized trial, there was no difference in ICU-acquired bloodstream infections caused by multidrug-resistant gram-negative bacteria (MDRGNB) among ventilated ICU patients given chlorhexidine 2% mouthwash, selective oropharyngeal decontamination (mouthpaste with colistin, tobramycin, and nystatin), or selective digestive tract decontamination (the same mouthpaste and gastrointestinal suspension with the same antibiotics), all applied 4 times daily. Bastiaan H. Wittekamp, MD, PhD, of University Medical Center Utrecht, the Netherlands, presents findings from the R-GNOSIS ICU trial at the European Society of Intensive Care Medicine (ESICM) 31st Annual Congress, LIVES 2018, on October 22 in Paris. Used with permission.