[Skip to Content]
[Skip to Content Landing]

In Vivo Autofluorescence Imaging of Photoreceptors in Stargardt Disease Type 1

Fluorescence adaptive optics scanning light ophthalmoscopy (AOSLO) can provide in vivo autofluorescence images with microscopic resolution to elucidate the cellular origin of abnormalities in Stargardt disease type 1. This video shows a comparison of autofluorescence and reflectance images from the same retinal location and demonstrates an abnormal autofluorescence structure more consistent in appearance with photoreceptor than retinal pigment epithelial cell reflectance, suggesting that photoreceptor damage mediated by the accumulation of lipofuscin precursors may precede retinal pigment epithelial cell death in Stargardt disease type 1.

We are currently experiencing technical difficulties that may affect log in and other features. Thank you for your understanding.

JN Learning™ is the home for CME and MOC from the JAMA Network. Search by specialty or US state and earn AMA PRA Category 1 Credit(s)™ from articles, audio, Clinical Challenges and more. Learn more about CME/MOC


Name Your Search

Save Search

Lookup An Activity


My Saved Searches

You currently have no searches saved.


My Saved Courses

You currently have no courses saved.