Effects of Vitamin D Supplementation On Outcomes In Patients With Gastrointestinal (GI) Cancer

Translational evidence suggests vitamin D has antineoplastic effects, and observational studies have shown an inverse association between serum vitamin D levels and colorectal cancer risk. However, clinical trials of vitamin D for cancer chemoprevention have had conflicting results. This video abstract summarizes findings from 2 clinical trials investigating whether vitamin D supplementation improves outcomes for patients with colorectal, gastric, and esophageal cancers.