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In a 2019 randomized trial, selepressin--a selective vasopressin V1a receptor agonist hypothesized to mitigate sepsis-induced vasodilatation, vascular leakage, and tissue edema because of its absence of V1b- or V2-mediated effects--did not improve vasopressor- and ventilator-free days at 30 days among patients with septic shock. Pierre-François Laterre, MD, of St. Luc University Hospital, Université Catholique de Louvain in Brussels, Belgium, presents findings from the SEPSIS-ACT trial at the European Society of Intensive Care Medicine (ESICM) 32nd Annual Congress, LIVES 2019, on October 2 in Berlin. Click the related article link for full trial details. Video used with permission.
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