Intraoperative assessment of oropharyngeal specimens is essential to effective oncologic surgery. This traditionally involves assessment of margin status with frozen section analysis. Unfortunately, this process is not perfect, and it can be hard to correlate histopathologic specimens to in vivo disease. Using adjunct intraoperative imaging to assist the surgeon’s resection has become an important new area of discovery. Wide-field optical coherence tomography is one of these novel adjuncts and can provide high-resolution images without affecting standard of care or deforming the specimen. The wide-field optical coherence tomography imagine process is demonstrated here using a tonsil cancer specimen.
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