A woman in her 50s presented with exertional dyspnea for 3 months and sudden syncope. Cardiac magnetic resonance imaging revealed a mobile mass in the right atrium and ventricle. Pathologic study confirmed a diagnosis of intravenous leiomyomatosis. Intravenous leiomyomatosis with intracardiac extension is a rare clinical condition that could be severely symptomatic and even life-threatening.
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